{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T02:53:51Z","timestamp":1761101631408},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2002,9,3]],"date-time":"2002-09-03T00:00:00Z","timestamp":1031011200000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2002,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\u03b1<jats:sup>+<\/jats:sup>\u2010Thalassemia (\u2212\u03b1) is prevalent throughout tropical and subtropical regions of world, whereas \u03b1<jats:sup>0<\/jats:sup>\u2010thalassemia (\u2212\u2212) occurs at higher frequency in Southeast Asia. Homozygosity for the \u03b1<jats:sup>0<\/jats:sup>\u2010thalassemia deletion (\u2212\u2212\/\u2212\u2212) is a serious health problem in Southeast Asia and the Philippines and is responsible for the majority of hydrops fetalis in this region. Asian immigration in United States has impacted the demography of genetic disease in U.S. As Asians comprise of 10% of all California births and represent a population at highest risk for \u03b1<jats:sup>0<\/jats:sup>\u2010thalassemia, we developed a rapid and efficient PCR approach to detect the common \u03b1<jats:sup>0<\/jats:sup>\u2010thalassemia deletions in Southeast Asians and Filipinos using newborn screening specimen. Am. J. Hematol. 71:56\u201358, 2002. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajh.10182","type":"journal-article","created":{"date-parts":[[2002,10,8]],"date-time":"2002-10-08T23:01:00Z","timestamp":1034118060000},"page":"56-58","source":"Crossref","is-referenced-by-count":6,"title":["Rapid confirmation of Southeast Asian and Filipino \u03b1\u2010thalassemia genotypes from newborn screening specimens"],"prefix":"10.1002","volume":"71","author":[{"given":"Urvashi","family":"Bhardwaj","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao\u2010Hua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Blackburn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda L.","family":"McCabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward R.B.","family":"McCabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,9,3]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V91.7.2213"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199705013361805"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00216149"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8652(199802)57:2<124::AID-AJH6>3.0.CO;2-Y"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8652(199901)60:1<80::AID-AJH17>3.0.CO;2-W"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320390314"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(05)70427-2"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1998.tb10515.x"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830190105"},{"key":"e_1_2_1_11_2","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/ajcp\/107.5.576","article-title":"Frequency of deletional \u03b1\u2010thalassemia genotypes in a predominantly Asian\u2010American population","volume":"107","author":"Hofgarter WT","year":"1997","journal-title":"Am J Clin Pathol"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1992.tb08180.x"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1182\/blood.V95.1.360","article-title":"Single\u2010tube multiplex PCR screen for common deletional determinants of \u03b1\u2010thalassemia","volume":"95","author":"Chong SS","year":"2000","journal-title":"Blood"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.1.2.99"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.10182","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.10182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T22:24:54Z","timestamp":1700259894000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.10182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,9]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2002,9]]}},"alternative-id":["10.1002\/ajh.10182"],"URL":"https:\/\/doi.org\/10.1002\/ajh.10182","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,9]]}}}