{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,15]],"date-time":"2024-09-15T12:48:12Z","timestamp":1726404492811},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2002,11,22]],"date-time":"2002-11-22T00:00:00Z","timestamp":1037923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2002,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a case of CD3\u2010negative, CD20\u2010positive T\u2010cell prolymphocytic leukemia (T\u2010PLL). The leukemic cells were of medium\u2010to\u2010large size, mature\u2010looking, and did not have cytoplasmic granules. The leukemic cells were negative for surface CD3, CD2, and CD7 and strongly positive for CD20. T\u2010cell lineage markers such as CD4, CD5, and cytoplasmic CD3 were also positive. A monoclonal rearrangement of the T\u2010cell receptor (TCR) \u03b2 chain gene was detected. CD3\u2010negative T\u2010PLL has been reported often, but CD20\u2010positive T\u2010PLL has not. We reviewed seven cases of CD20\u2010positive immature and mature T\u2010cell leukemias, including the present case. Three were immature T\u2010cell leukemias (acute lymphoblastic leukemia), and four were mature T\u2010cell leukemias (granular lymphocytic leukemia, small lymphocytic lymphoma\/chronic lymphocytic leukemia, adult T\u2010cell leukemia, and the present case). Splenomegaly was a common feature. However, our case alone had \u201cbright\u201d CD20 expression on the leukemic cells. This is the first report of CD20<jats:sup>+<\/jats:sup> T\u2010PLL. Am. J. Hematol. 71:331\u2013335, 2002. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajh.10224","type":"journal-article","created":{"date-parts":[[2002,11,25]],"date-time":"2002-11-25T13:57:37Z","timestamp":1038232657000},"page":"331-335","source":"Crossref","is-referenced-by-count":15,"title":["CD3\u2010negative, CD20\u2010positive T\u2010cell prolymphocytic leukemia: Case report and review of the literature"],"prefix":"10.1002","volume":"71","author":[{"given":"Kenji","family":"Tamayose","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naotake","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Ando","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Sugimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Oshimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,11,22]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1998.tb01231.x"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.990180206"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V78.12.3269.3269"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/107327489800500102"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2257.1995.tb01272.x"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1998.00552.x"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1998.00884.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8652(200101)66:1<39::AID-AJH1005>3.0.CO;2-U"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1182\/blood.V86.3.1163.1163","article-title":"True T\u2010cell chronic lymphocytic leukemia: a morphologic and immunophenotypic study of 25 cases","volume":"86","author":"Hoyer JD","year":"1995","journal-title":"Blood"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0320(19980415)34:2<71::AID-CYTO2>3.0.CO;2-F"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.1071"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.22.13099"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1996.tb01096.x"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.10224","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.10224","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T12:40:11Z","timestamp":1700397611000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.10224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,11,22]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,12]]}},"alternative-id":["10.1002\/ajh.10224"],"URL":"https:\/\/doi.org\/10.1002\/ajh.10224","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"type":"print","value":"0361-8609"},{"type":"electronic","value":"1096-8652"}],"subject":[],"published":{"date-parts":[[2002,11,22]]}}}