{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T12:40:18Z","timestamp":1700224818841},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2003,7,18]],"date-time":"2003-07-18T00:00:00Z","timestamp":1058486400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2003,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Heparin\u2010induced thrombocytopenia (HIT) and idiopathic thrombocytopenic purpura (ITP) are separate and well\u2010recognized clinical syndromes, 10both having potential for disastrous outcomes. Sequential occurrence of these two diseases has not been reported in the literature. We report herein two patients who were initially diagnosed as having HIT but whose later clinical course was similar to ITP. Although dysfunction of immune system seems to play a role, the precise mechanisms for the development of these diseases are unclear. As both conditions have different natural histories and require different treatment modalities, it is important to recognize that these two diseases may be seen sequentially. Am. J. Hematol. 73:290\u2013293, 2003. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajh.10368","type":"journal-article","created":{"date-parts":[[2003,7,21]],"date-time":"2003-07-21T10:11:54Z","timestamp":1058782314000},"page":"290-293","source":"Crossref","is-referenced-by-count":2,"title":["Two patients with heparin\u2010induced thrombocytopenia followed by idiopathic (immune) thrombocytopenic purpura: Case Report"],"prefix":"10.1002","volume":"73","author":[{"given":"Faisal","family":"Waheed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nauman","family":"Naseer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tauseef","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John C.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,7,18]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-85-2-155"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199505183322003"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.50.1.129"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-136-3-200202050-00009"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1614206"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.1997.d01-1008.x"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830190406"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V88.1.3.3"},{"issue":"1","key":"e_1_2_1_10_2","first-page":"s50","article-title":"Evaluation of a platelet glycoprotein (GP) specific assay in the diagnosis of autoimmune thrombocytopenia","volume":"94","author":"McFarland JG","year":"1999","journal-title":"Blood"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1993.tb03150.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1055\/s-0038-1642496","article-title":"Heparin\u2010associated thrombocytopenia: the effect of various IVIG preparations on antibody mediated platelet activation\u2014a possible new indication for high dose IVIG","volume":"71","author":"Greinacher A","year":"1994","journal-title":"Thromb Haemost"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1023238915316"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1984.tb00484.x"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7053569"},{"key":"e_1_2_1_16_2","first-page":"356","article-title":"Platelet specific alloantigens","volume":"11","author":"Davis GL","year":"1998","journal-title":"Clin Lab Sci"},{"key":"e_1_2_1_17_2","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1182\/blood.V92.5.1526","article-title":"Heparin induced thrombocytopenia: new insights into the impact of Fc gamma RIIa\u2010R\u2010H131 polymorphism","volume":"92","author":"Carlsson LE","year":"1998","journal-title":"Blood"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2143(97)90022-6"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8652(199601)51:1<73::AID-AJH12>3.0.CO;2-C"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/jca.1031"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.10368","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.10368","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T12:25:05Z","timestamp":1700223905000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.10368"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,7,18]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,8]]}},"alternative-id":["10.1002\/ajh.10368"],"URL":"https:\/\/doi.org\/10.1002\/ajh.10368","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,7,18]]}}}