{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T06:25:55Z","timestamp":1764224755068},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,7,23]],"date-time":"2004-07-23T00:00:00Z","timestamp":1090540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2004,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Infectious mononucleosis (IM) due to all causes is characterized by atypical lymphocytosis. We sought to compare hematologic parameters of infectious mononucleosis due to Epstein\u2013Barr virus (EBV) infection (heterophile antibody (HA) positive) with mononucleosis due to other causes. Mono\u2010Latex Slide Agglutination Test results and complete blood counts (CBC) of 147 patients with mononucleosis were retrospectively analyzed. Leukocyte count, absolute lymphocyte count, and presence of atypical lymphocytes in EBV\u2010positive and EBV\u2010negative groups were statistically compared. We analyzed 68 EBV\u2010positive and 79 EBV\u2010negative cases. EBV\u2010positive patients were significantly younger than EBV\u2010negative patients were. Mean total WBC count and mean absolute lymphocyte count were significantly higher in EBV\u2010positive patients. Absolute lymphocytosis, absolute leukocytosis, and atypical lymphocytosis were also significantly more frequent in EBV\u2010positive patients. Leukopenia was more frequently seen in EBV\u2010negative patients. Am. J. Hematol. 76:315\u2013318, 2004. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajh.20119","type":"journal-article","created":{"date-parts":[[2004,7,23]],"date-time":"2004-07-23T17:02:49Z","timestamp":1090602169000},"page":"315-318","source":"Crossref","is-referenced-by-count":15,"title":["Hematologic differences in heterophile\u2010positive and heterophile\u2010negative infectious mononucleosis"],"prefix":"10.1002","volume":"76","author":[{"given":"K.C.","family":"Ventura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.D.","family":"Hudnall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,7,23]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198704010-01011"},{"key":"e_1_2_1_3_2","first-page":"1755","volume-title":"Textbook of pediatric infectious diseases","author":"Sumaya CV","year":"1998"},{"key":"e_1_2_1_4_2","first-page":"1599","volume-title":"Principles and practice of infectious diseases","author":"Schooley RT","year":"2000"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-193201000-00010"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.59.1.94"},{"issue":"12","key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"3240","DOI":"10.1128\/jcm.34.12.3240-3241.1996","article-title":"Evaluations of enzyme\u2010linked immunosorbent assay procedure for determining specific Epstein\u2013Barr virus serology and of rapid test kits for diagnosis of infectious mononucleosis","volume":"34","author":"Gerber MA","year":"1996","journal-title":"J Clin Microbiol"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0065-3101(22)00754-X","article-title":"Infectious mononucleosis","volume":"22","author":"Karzon DT","year":"1976","journal-title":"Adv Pediatr"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02122009"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0928-0197(96)00245-0"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1981.02130320013004"},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1093\/ajcp\/87.4.485","article-title":"Hematologic parameters and leukocyte histogram in infectious mononucleosis","volume":"87","author":"Lofness KG","year":"1987","journal-title":"Am J Clin Pathol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-4453(81)91882-X"},{"key":"e_1_2_1_14_2","first-page":"875","article-title":"Infectious mononucleosis in an outpatient population. 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