{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T02:42:53Z","timestamp":1700188973845},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,7,23]],"date-time":"2004-07-23T00:00:00Z","timestamp":1090540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2004,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Chronic active Epstein\u2013Barr virus infection (CAEBV) is a heterogeneous EBV\u2010related disorder, ranging from mild\/moderate forms to rapidly lethal disorders. The lethal form of CAEBV is characterized by multiple organ failure, hemophagocytic syndrome, and development of lymphomas. Allogeneic stem cell transplantation is considered as the only potentially curative treatment for the lethal form of CAEBV, but it is not always desirable because of the high incidence of regimen\u2010related toxicities. A 17\u2010year\u2010old female with CAEBV, who was refractory to conventional therapies and considered to be unable to receive a myeloablative regimen because of multiple organ dysfunction, underwent allogeneic nonmyeloablative stem cell transplantation (allo\u2010NST) before developing a hematological malignancy. She has been well without any signs of CAEBV for 27 months after allo\u2010NST, and we confirmed that specific cytotoxic T lymphocyte activity against EBV was reconstituted. This outcome suggests that allo\u2010NST can control CAEBV by reconstituting the host immunity against EBV. Am. J. Hematol. 76:368\u2013372, 2004. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajh.20121","type":"journal-article","created":{"date-parts":[[2004,7,23]],"date-time":"2004-07-23T17:03:53Z","timestamp":1090602233000},"page":"368-372","source":"Crossref","is-referenced-by-count":14,"title":["Successful control of Epstein\u2013Barr virus (EBV)\u2010infected cells by allogeneic nonmyeloablative stem cell transplantation in a patient with the lethal form of chronic active EBV 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