{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:58:22Z","timestamp":1784044702756,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,11,18]],"date-time":"2004-11-18T00:00:00Z","timestamp":1100736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2004,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Human T\u2010cell lymphotropic virus type 1 (HTLV\u20101) is endemic in certain regions of the world where it is associated with lymphoid malignancies. Herein we aim to describe the seroprevalence of HTLV\u20101 in lymphoid malignancies in Dominica. We carried out a 10\u2010year retrospective study of histologically proven hematologic malignancies and HTLV\u20101 seropositivity at the Princess Margaret Hospital, Dominica. Ninety\u2010eight cases were reviewed (59% males, 41% females), ranging in age from 3 to 91 years. HTLV\u20101 was seropositive in 38.6% (31\/80) of all hematologic malignancies. Three of 6 cases of Hodgkin disease (50%), 16 of 36 (44.4%) of non\u2010Hodgkin lymphoma, and 3 out of 8 unclassified lymphomas (37.5%) were seropositive; all 6 cases (100%) of acute adult T\u2010cell leukemia\/lymphoma (ATLL) were seropositive. One case each of chronic lymphocytic leukemia and myeloproliferative disorder was seropositive. HTLV\u20101\u2010seropositive lymphomas presented at a younger age than did seronegative cases. Thus, HTLV\u20101 is significantly associated with lymphoid malignancies in Dominica, and further studies are needed before a causal relationship with Hodgkin disease can be established. Am. J. Hematol. 77:336\u2013339, 2004. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajh.20208","type":"journal-article","created":{"date-parts":[[2004,11,18]],"date-time":"2004-11-18T21:53:11Z","timestamp":1100814791000},"page":"336-339","source":"Crossref","is-referenced-by-count":6,"title":["Human T\u2010cell lymphotropic virus type 1 (HTLV\u20101) and lymphoid malignancies in Dominica: A seroprevalence study"],"prefix":"10.1002","volume":"77","author":[{"given":"Olayinka A.","family":"Adedayo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sani M.","family":"Shehu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,11,18]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.77.12.7415"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V50.3.481.481"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910290606"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.8.2534"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.15.1.15"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.6981847"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198608073150606"},{"key":"e_1_2_1_9_2","first-page":"252","article-title":"AIDS\u2010associated lymphomas (AIDS series)","volume":"12","author":"Gaidano G","journal-title":"Postgrad Doctor Caribbean"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910430214"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)92734-5"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.1992.tb00092.x"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)90038-X"},{"key":"e_1_2_1_14_2","first-page":"1116","article-title":"Prevalence of serum and salivatory antibodies to HTLV\u20101 in Sj\u00f6gren's syndrome","volume":"377","author":"Terada K","year":"1990","journal-title":"Lancet"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)92896-P"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2001.65.650"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(97)70353-0"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.2883731"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)90236-4"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.79.932.341"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02981984"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042560-199707010-00008"},{"key":"e_1_2_1_23_2","first-page":"36","article-title":"The immunophenotyping of non\u2010Hodgkins lymphoma in formalin\u2010fixed paraffin\u2010embedded tissue","volume":"39","author":"Williams E","year":"1990","journal-title":"West Indian Med J"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042560-199600001-00005"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.3109\/10428199209053580"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.20208","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.20208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T22:04:17Z","timestamp":1700172257000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.20208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11,18]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2004,12]]}},"alternative-id":["10.1002\/ajh.20208"],"URL":"https:\/\/doi.org\/10.1002\/ajh.20208","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,11,18]]}}}