{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T22:43:29Z","timestamp":1700174609105},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,5,31]],"date-time":"2005-05-31T00:00:00Z","timestamp":1117497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2005,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 41\u2010year\u2010old Caucasian female was diagnosed with a CD3<jats:sup>+<\/jats:sup> CD4<jats:sup>+<\/jats:sup> CD8<jats:sup>+<\/jats:sup> variant of lymphoproliferative disorder of granular lymphocytes (LDGL) in the third year of remission following treatment of stage III\u2010B Hodgkin lymphoma (HL). The patient was asymptomatic at diagnosis, without clinical evidence of immune disorder or recurrence of HL. Diagnosis was made incidentally, secondary to lymphocytosis discovered on a routine follow\u2010up post HL therapy. Clonal chromosomal abnormalities were seen in 20% of peripheral blood lymphocytes with a karyotype 46, XX, t(2;6;2;11) (p13;q23;q24;q23). The breakpoint on 11q23 is distal to the MLL gene as shown by fluorescence in situ hybridization (FISH) analysis. To our knowledge, this is the first report of variant LDGL in association with HL treatment with documented clonal chromosomal abnormalities. Am. J. Hematol. 79:128\u2013131, 2005. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajh.20312","type":"journal-article","created":{"date-parts":[[2005,5,31]],"date-time":"2005-05-31T20:17:29Z","timestamp":1117570649000},"page":"128-131","source":"Crossref","is-referenced-by-count":0,"title":["Variant lymphoproliferative disorder of granular lymphocytes (LDGL) following Hodgkin lymphoma"],"prefix":"10.1002","volume":"79","author":[{"given":"Brian Douglas","family":"Jenkins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Snower","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anwar","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayad","family":"Al\u2010Katib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,31]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.153.3.569"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2257.1997.00217.x"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V89.1.256"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.138.2.274"},{"key":"e_1_2_1_6_2","first-page":"936","article-title":"Large granular lymphocytosis","volume":"83","author":"Zambello R","year":"1998","journal-title":"Haematologica"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/21548331.1998.11443695"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V84.5.1361.1361"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19871215)60:12<2971::AID-CNCR2820601220>3.0.CO;2-O"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198709000-00005"},{"key":"e_1_2_1_11_2","first-page":"617","article-title":"Granular lymphocyte proliferative disorders: report of 12 cases and review of the literature","volume":"2","author":"Oshimi K","year":"1988","journal-title":"Leukemia"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.1125"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.10046"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1996.00399.x"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2002.03564.x"},{"key":"e_1_2_1_16_2","first-page":"2403","volume-title":"Cancer medicine","author":"Rheingold SR","year":"2002"},{"key":"e_1_2_1_17_2","first-page":"2939","volume-title":"Cancer: principles and practice of oncology. 6th edition","author":"Van Leeuwen FE","year":"2001"},{"key":"e_1_2_1_18_2","first-page":"937","article-title":"The incidence of secondary leukemias","volume":"84","author":"Leone G","year":"1999","journal-title":"Haematologica"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830500403"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19920201)69:3<778::AID-CNCR2820690327>3.0.CO;2-E"},{"key":"e_1_2_1_21_2","first-page":"696","article-title":"Permanent large granular lymphocytosis in the blood of splenectomized individuals without concomitant increase of in vitro natural killer cell cytotoxicity","volume":"63","author":"Kelemen G","year":"1986","journal-title":"Clin Exp Immunol"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00320037"},{"issue":"8","key":"e_1_2_1_23_2","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1007\/s00705-004-0311-1","article-title":"High frequency of Epstein Barr virus latent membrane protein\u20101 30 bp deletion in a series of pediatric malignancies in Argentina","volume":"149","author":"Chabay P","year":"2004","journal-title":"Arch Virol"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-0538"},{"issue":"4","key":"e_1_2_1_25_2","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1182\/blood.V100.4.1449.h81602001449_1449_1453","article-title":"Blockade of Fas\u2010dependent apoptosis by soluble Fas in LGL leukemia","volume":"100","author":"Liu JH","year":"2002","journal-title":"Blood"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.20312","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.20312","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T22:23:19Z","timestamp":1700173399000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.20312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5,31]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["10.1002\/ajh.20312"],"URL":"https:\/\/doi.org\/10.1002\/ajh.20312","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,5,31]]}}}