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A limited autopsy revealed presence of breast cancer with rib metastases. Though severe deficiency of von Willebrand factor\u2010cleaving protease was initially proposed as a key pathogenetic factor for thrombotic thrombocytopenic purpura, subsequent studies involving patients with cancer\u2010associated TMA did not find as severe a deficiency of von Willebrand factor\u2010cleaving protease as is seen in idiopathic cases of thrombotic thrombocytopenic purpura. Here we address one approach of management of these patients with cancer\u2010associated TMA. Am. J. Hematol., 2006. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajh.20783","type":"journal-article","created":{"date-parts":[[2006,10,10]],"date-time":"2006-10-10T23:07:37Z","timestamp":1160521657000},"page":"295-298","source":"Crossref","is-referenced-by-count":50,"title":["Management of cancer\u2010associated thrombotic microangiopathy: What is the right approach?"],"prefix":"10.1002","volume":"82","author":[{"given":"Theresa L.","family":"Werner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neeraj","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather M.","family":"Carney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George 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