{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T19:51:55Z","timestamp":1789761115860,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2007,6,14]],"date-time":"2007-06-14T00:00:00Z","timestamp":1181779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Ocular adnexal lymphoma (OAL) is a mostly extranodal marginal zone lymphoma (EMZL). Recent findings have suggested an association between <jats:italic>Chlamydia psittaci (Cp<\/jats:italic>) infection and OAL. We sought to confirm this issue and to analyze the clinicopathologic characteristics of OAL in Korea. Between 1993 and 2004, 33 OAL cases were identified at the Asan Medical Center, Seoul, Korea. DNA was extracted from paraffin\u2010embedded tissues, and touchdown enzyme time release polymerase chain reaction was performed to identify three <jats:italic>Chlamydia<\/jats:italic> species (<jats:italic>Cp, C. tracomatis,<\/jats:italic> and <jats:italic>C. pneumoniae<\/jats:italic>). The same procedures were also performed in 21 samples from patients with non\u2010neoplastic ocular adnexal disease (NNOAD). All OAL cases were EMZL. <jats:italic>Cp<\/jats:italic> DNA was detected in 26\/33 (79%) OAL samples compared with 5\/21 (23%) NNOAD samples (<jats:italic>P<\/jats:italic> &lt; 0.001). With a median follow\u2010up of 38.5 months (range: 1\u2013105 months), the 5\u2010year progression\u2010free survival (PFS) and overall survival (OS) rates of OAL patients were 72% and 93%, respectively. Clinicopathologic characteristics, recurrence rate, PFS, and OS were not associated with <jats:italic>Cp<\/jats:italic> infection. Our study demonstrates an association between OAL and <jats:italic>Cp<\/jats:italic> infection in Korea, suggesting that <jats:italic>Cp<\/jats:italic> plays a role as a causative antigen in Korean OAL patients. Am. J. Hematol., 2007. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajh.20962","type":"journal-article","created":{"date-parts":[[2007,6,14]],"date-time":"2007-06-14T18:47:37Z","timestamp":1181846857000},"page":"821-823","source":"Crossref","is-referenced-by-count":65,"title":["<i>Chlamydia psittaci<\/i> infection and clinicopathologic analysis of ocular adnexal lymphomas in Korea"],"prefix":"10.1002","volume":"82","author":[{"given":"Changhoon","family":"Yoo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min\u2010Hee","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jooryung","family":"Huh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Hyun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hye 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