{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T10:21:24Z","timestamp":1787653284657,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2008,10,20]],"date-time":"2008-10-20T00:00:00Z","timestamp":1224460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The unique historical aspects of Pelger and Huet's discovery of the Pelger\u2010Huet cell highlight the diagnostic challenge that this morphologic finding presents to the physician. Making the diagnosis of the benign autosomal dominant anomaly is complicated by the morphologically similar pseudo\u2010Pelger\u2010Huet cell, which can signify underlying myeloid dsyplasia. This article relates the history of the Pelger\u2010Huet anomaly as well as describes the clinical significance and diagnostic workup for the finding of a Pelger\u2010Huet cell on peripheral smear. Am. J. Hematol., 2009. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajh.21320","type":"journal-article","created":{"date-parts":[[2008,10,20]],"date-time":"2008-10-20T18:08:18Z","timestamp":1224526098000},"page":"116-119","source":"Crossref","is-referenced-by-count":44,"title":["Historical perspective and clinical implications of the Pelger\u2010Huet cell"],"prefix":"10.1002","volume":"84","author":[{"given":"John M.","family":"Cunningham","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mrinal M.","family":"Patnaik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dale E.","family":"Hammerschmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory M.","family":"Vercellotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,11,18]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"1178","volume":"72","author":"Pelger K","year":"1928","journal-title":"Ndld Tschr Geneesk"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01758934"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1093\/ajcp\/14.10.544","article-title":"The Pelger\u2010Huet's familiar nuclear anomaly of the leukocytes","volume":"14","author":"Van Der Sar A","year":"1944","journal-title":"Am J Clin Pathol"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/37.3.294"},{"key":"e_1_2_1_6_2","unstructured":"KarlH.Die besondere Haufung vong Merkmalstragern der Pelger\u2010Huet\u2010Kernanomalie der Leukozyten in Gelenau im Erzgebirge Thesism. 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