{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T09:36:11Z","timestamp":1789205771652,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2010,5,5]],"date-time":"2010-05-05T00:00:00Z","timestamp":1273017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1002\/ajh.21754","type":"journal-article","created":{"date-parts":[[2010,5,5]],"date-time":"2010-05-05T19:25:07Z","timestamp":1273087507000},"page":"616-619","source":"Crossref","is-referenced-by-count":17,"title":["Phase I\/II study of single\u2010agent bortezomib for the treatment of patients with myelofibrosis. Clinical and biological effects of proteasome inhibition"],"prefix":"10.1002","volume":"85","author":[{"given":"Giovanni","family":"Barosi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Gattoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Guglielmelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Campanelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Facchetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Fisogni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Goldberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Marchioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald","family":"Hoffman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro M.","family":"Vannucchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,6,10]]},"reference":[{"key":"e_1_2_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-07-170449"},{"key":"e_1_2_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-2339"},{"key":"e_1_2_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.165.4.2271"},{"key":"e_1_2_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1309\/4YGKED5LWFW4AVDV"},{"key":"e_1_2_1_3_1_6_2","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1111\/j.1365-2141.2004.04829.x","article-title":"Spleen neoangiogenesis in patients with myelofibrosis with myeloid metaplasia","volume":"24","author":"Barosi G","year":"2004","journal-title":"Br J Haematol"},{"key":"e_1_2_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-03-009746"},{"key":"e_1_2_1_3_1_8_2","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1038\/leu.2008.32","article-title":"Bortezomib therapy in myelofibrosis: A phase II clinical trial","volume":"22","author":"Mesa RA","year":"2008","journal-title":"Leukemia"},{"key":"e_1_2_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1414.004"},{"key":"e_1_2_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdn656"},{"key":"e_1_2_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.11325"},{"key":"e_1_2_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.11.4207"},{"key":"e_1_2_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-06-2511"},{"key":"e_1_2_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2008.001537"},{"key":"e_1_2_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.14.1.65"},{"key":"e_1_2_1_3_1_16_2","first-page":"1243","article-title":"Effects of the proteasome inhibitor PS\u2010341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts","volume":"1","author":"Nawrocki ST","year":"2002","journal-title":"Mol Cancer Ther"},{"key":"e_1_2_1_3_1_17_2","first-page":"1419","article-title":"Novel proteasome inhibitor PS\u2010341 inhibits activation of nuclear factor\u2010kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma","volume":"7","author":"Sunwoo JB","year":"2001","journal-title":"Clin Cancer Res"},{"key":"e_1_2_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2007.04.012"},{"key":"e_1_2_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1159\/000087894"},{"key":"e_1_2_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2007.11.017"},{"key":"e_1_2_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403592"},{"key":"e_1_2_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2008.385"},{"key":"e_1_2_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.13783"},{"key":"e_1_2_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-05-2118"},{"key":"e_1_2_1_3_1_25_2","first-page":"1128","article-title":"EUMNET European consensus on grading bone marrow fibrosis and assessment of cellularity","volume":"90","author":"Thiele J","year":"2005","journal-title":"Haematologica"},{"key":"e_1_2_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0320(19980415)34:2<61::AID-CYTO1>3.0.CO;2-F"},{"key":"e_1_2_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.12165"},{"key":"e_1_2_1_3_1_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcmd.2007.01.003"},{"key":"e_1_2_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404854"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.21754","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.21754","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T03:45:49Z","timestamp":1700624749000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.21754"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,10]]},"references-count":28,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["10.1002\/ajh.21754"],"URL":"https:\/\/doi.org\/10.1002\/ajh.21754","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,10]]}}}