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Seventy\u2010nine percent had intermediate\/unfavorable karyotype and 79% had a high comorbidity. Overall response was 55% [complete response (CR) 47%] and 37% were refractory. CR rate was 52% in patients between 71 and 79 years of age and 38% in patients 80 years or older. The 4\u2010week induction mortality was 16% (8% in patients between 70 and 79 years of age and 32% in patients 80 years or older). Overall survival (OS) at 3 years was 22% (31.3% in patients between 70 and 79 years and 15.4% in patients 80 years or older). Relapse\u2010free survival (RFS) at 3 years was 15%. A total of 65 cycles (47 as induction and 18 as consolidation) were administered, 46 of them (70%) in an outpatient setting. In summary, this FLAGIDA\u2010lite protocol is an effective and well\u2010tolerated option for patients between the ages of 70 and 79 years with acute myeloid leukemia or refractory anemia with excess blasts\u20102 and is usually feasible as outpatient treatment, but is not beneficial for most patients 80 years or older. Am. J. Hematol., 2012. \u00a9 2011 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ajh.22192","type":"journal-article","created":{"date-parts":[[2011,9,21]],"date-time":"2011-09-21T21:29:14Z","timestamp":1316640554000},"page":"42-44","source":"Crossref","is-referenced-by-count":1,"title":["FLAGIDA\u2010lite is an effective regimen for patients between 70 and 80 years with acute myeloid leukemia or refractory anemia with excess blasts\u20102 and is feasible as outpatient 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