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Men were affected twice as common as women, at a median age of 59 (23\u201389) years. None had a history of celiac disease. The sites of involvement were small bowel and stomach (5%), small bowel (63%), small and large bowel (16%), and large bowel (18%). Common presenting features were bowel perforation (34%), pain (32%), and obstruction (21%). Lymphomas showed monomorphic neoplastic lymphoid infiltrates that were CD3<jats:sup>+<\/jats:sup> (100%), CD56<jats:sup>+<\/jats:sup> (91%), TIA\u20101<jats:sup>+<\/jats:sup> (96%), CD4<jats:sup>\u2013<\/jats:sup>CD8<jats:sup>+<\/jats:sup> (63%), CD4<jats:sup>+<\/jats:sup>CD8<jats:sup>+<\/jats:sup> (19%), CD4<jats:sup>\u2013<\/jats:sup>CD8<jats:sup>\u2013<\/jats:sup> (16%), and CD4<jats:sup>+<\/jats:sup>CD8<jats:sup>\u2013<\/jats:sup> (3%). Epstein Barr virus was demonstrable in three cases. Despite chemotherapy and\/or surgical resection, the overall response and complete response rates were poor at 46% and 38%. The median overall survival (OS) was 7 months and progression\u2010free\u2010survival (PFS) 1 month. Five patients underwent hematopoietic stem cell transplantation all were alive. Age and the prognostic index for peripheral T\u2010cell lymphoma were not prognostically significant. Good performance status was associated with better OS (<jats:italic>P<\/jats:italic> = 0.03), and response to initial treatment led to better OS and PFS (<jats:italic>P<\/jats:italic> &lt; 0.001). Am. J. Hematol. 87:663\u2013668, 2012. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ajh.23213","type":"journal-article","created":{"date-parts":[[2012,4,3]],"date-time":"2012-04-03T16:18:09Z","timestamp":1333469889000},"page":"663-668","source":"Crossref","is-referenced-by-count":154,"title":["Type II enteropathy\u2010associated T\u2010cell lymphoma: A multicenter analysis from the Asia Lymphoma Study Group"],"prefix":"10.1002","volume":"87","author":[{"given":"Eric","family":"Tse","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harinder","family":"Gill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Loong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seok 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