{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T03:42:45Z","timestamp":1789530165956,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,4,10]],"date-time":"2014-04-10T00:00:00Z","timestamp":1397088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:p>The impact of race\/ethnicity and the additional factors of age, sex, and socioeconomic status (SES) on follicular lymphoma (FL) outcomes have not been comprehensively studied and are not well defined. We examined population\u2010based FL data from &gt;18,000 patients in SEER\u201013 (1992\u20132009) investigating race\/ethnicity and the impact of relevant factors including sex, age, and SES. Further, we compared data over two consecutive periods: Era\u20101 (1992\u20132000, <jats:italic>n<\/jats:italic>\u2009=\u20098,355) and Era\u20102 (2001\u20132009, <jats:italic>n<\/jats:italic>\u2009=\u200910,475). We identified 18,830 FL patients (White: <jats:italic>n<\/jats:italic>\u2009=\u200915,116; Hispanic: <jats:italic>n<\/jats:italic>\u2009=\u20091,627; Asian\/Pacific Islander (A\/PI): <jats:italic>n<\/jats:italic>\u2009=\u20091,002; and Black: <jats:italic>n<\/jats:italic>\u2009=\u2009846). Median ages (years) differed significantly by race\/ethnicity: White: 62.1, Hispanic: 57.3, A\/PI: 60.7, and Black: 56.8 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01 each race versus White). Overall survival (OS) was superior in Era\u20102 versus Era\u20101 for all patients (5\u2010year: 76.7% versus 67.4%, respectively, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Further, survival was significantly improved for all age groups &lt;80 years, for males (<jats:italic>P<\/jats:italic>\u2009=\u20090.0019), and females (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) across eras. Females had superior OS compared with males in Era\u20101 (<jats:italic>P<\/jats:italic>\u2009=\u20090.004), but not in Era\u20102. Additionally, all races, except A\/PI, had improved 5\u2010year OS rates from Era\u20101 to Era\u20102. Finally, OS improved across eras for lower and higher SES populations; however those with higher SES were superior to lower SES patients in both eras. In conclusion, and in the largest comprehensive evaluation of US\u2010based FL patients to date, we show that despite improvements in OS for FL over time, critical disparities across races\/ethnicities, sex, and age groups remain in the modern era and warrant further studies. Am. J. Hematol. 89:633\u2013638, 2014. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ajh.23708","type":"journal-article","created":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T06:54:36Z","timestamp":1394780076000},"page":"633-638","source":"Crossref","is-referenced-by-count":43,"title":["The impact of race, age, and sex in follicular lymphoma: A comprehensive SEER analysis across consecutive treatment eras"],"prefix":"10.1002","volume":"89","author":[{"given":"Chadi","family":"Nabhan","sequence":"first","affiliation":[{"name":"Section of Hematology and Oncology Department of Medicine The University of Chicago Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Briseis","family":"Aschebrook\u2010Kilfoy","sequence":"additional","affiliation":[{"name":"Division of Epidemiology Department of Health Studies The University of Chicago Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian C\u2010H","family":"Chiu","sequence":"additional","affiliation":[{"name":"Division of Epidemiology Department of Health Studies The University of Chicago Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly","family":"Kruczek","sequence":"additional","affiliation":[{"name":"Loyola University of Chicago Maywood Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonali M.","family":"Smith","sequence":"additional","affiliation":[{"name":"Section of Hematology and Oncology Department of Medicine The University of Chicago Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew M.","family":"Evens","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology Tufts University School of Medicine Boston 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