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The six members of the hematopathology panel evaluated 98 BM specimens independently and in a blinded fashion without knowledge of clinical data. The specimens included 48 cases of mPV according to the originally published hemoglobin threshold values for this entity (male: 16.0\u201318.4 g\/dL, female: 15.0\u201316.4 g\/dL), 31 cases with overt PV according to the updated 2016 WHO criteria, and 19 control cases. The latter group included cases of <jats:italic>JAK2<\/jats:italic>\u2010mutated ET, primary myelofibrosis, myelodysplastic syndrome, and various reactive conditions. Inter\u2010rater agreement between the panelists was very high (overall agreement 92.6%, kappa 0.812), particularly with respect to separating mPV from ET. Virtually all cases of mPV were correctly classified as PV according to their BM morphology. In conclusion, a central blinded review of histology slides by six hematopathologists demonstrated that highly reproducible specific histological pattern characterize PV and confirmed the notion that there are no significant differences between mPV and overt PV in relation to BM morphology.<\/jats:p>","DOI":"10.1002\/ajh.24837","type":"journal-article","created":{"date-parts":[[2017,7,7]],"date-time":"2017-07-07T12:41:20Z","timestamp":1499431280000},"page":"1062-1067","source":"Crossref","is-referenced-by-count":31,"title":["European LeukemiaNet study on the reproducibility of bone marrow features in masked polycythemia vera and differentiation from essential thrombocythemia"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5450-4840","authenticated-orcid":false,"given":"Hans Michael","family":"Kvasnicka","sequence":"first","affiliation":[{"name":"Senckenberg Institute of Pathology, University of Frankfurt  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attilio","family":"Orazi","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Weill Cornell Medical College New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juergen","family":"Thiele","sequence":"additional","affiliation":[{"name":"Institute of Pathology, University of Cologne Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Barosi","sequence":"additional","affiliation":[{"name":"Center for the Study of Myelofibrosis, Biotechnology Research Area, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S. 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