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In this review, we discuss several areas relevant to the care of JWs, including the current literature on \u201cbloodless\u201d medical care in the setting of perioperative and intraoperative management, acute blood loss, trauma, pregnancy, and malignancy. We have found that medical and administrative efforts in the form of bloodless medicine and surgery programs can be instrumental in helping to reduce risks of morbidity and mortality in these patients. Planning prior to an anticipated event associated with blood loss or anemia (such as elective surgery, pregnancy, and chemotherapy) is critical. Specifically, bloodless medicine programs should prioritize vigilant early screening and management of anemias, early establishment of patient wishes regarding transfusion, and the incorporation of those wishes into multidisciplinary medical and surgical care. Although there are now a variety of human\u2010based and nonhuman\u2010based products available as transfusion alternatives, the degree and quality of evidence to support their use varies significantly between products and is also largely dependent on the clinical setting.<\/jats:p>","DOI":"10.1002\/ajh.24889","type":"journal-article","created":{"date-parts":[[2017,8,17]],"date-time":"2017-08-17T08:39:04Z","timestamp":1502959144000},"page":"1370-1381","source":"Crossref","is-referenced-by-count":51,"title":["Treatment of individuals who cannot receive blood products for religious or other reasons"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0676-9342","authenticated-orcid":false,"given":"Carlton D.","family":"Scharman","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Oregon Health and Science University Portland 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