{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T01:45:12Z","timestamp":1790905512264,"version":"4.1.0"},"reference-count":193,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T00:00:00Z","timestamp":1602547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Despite its essential role in many biological processes, iron is toxic when in excess due to its propensity to generate reactive oxygen species. To prevent diseases associated with iron deficiency or iron loading, iron homeostasis must be tightly controlled. Intracellular iron content is regulated by the Iron Regulatory Element\u2010Iron Regulatory Protein (IRE\u2010IRP) system, whereas systemic iron availability is adjusted to body iron needs chiefly by the hepcidin\u2010ferroportin (FPN) axis. Here, we aimed to review advances in the field that shed light on cell\u2010type\u2010specific regulatory mechanisms that control or modify systemic and local iron balance, and how shifts in cellular iron levels may affect specialized cell functions.<\/jats:p>","DOI":"10.1002\/ajh.26001","type":"journal-article","created":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T05:45:39Z","timestamp":1600407939000},"page":"110-127","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["Cell\u2010type\u2010specific insights into iron regulatory processes"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9095-9597","authenticated-orcid":false,"given":"Katarzyna","family":"Mleczko\u2010Sanecka","sequence":"first","affiliation":[{"name":"International Institute of Molecular and Cell Biology  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Silvestri","sequence":"additional","affiliation":[{"name":"Regulation of Iron Metabolism Unit, Division of Genetics and Cell Biology IRCCS San Raffaele Scientific Institute  Milan Italy"},{"name":"Vita\u2010Salute San Raffaele University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.12.034"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60692-4"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(13)70001-9"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/HS9.0000000000000040"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041534"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/87.5.1374"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-13-0145"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz112"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-12-4844"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.050773"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1104742"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-05-786590"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2014.00176"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10534-019-00191-7"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2020.02.011"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2013.00034"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3453"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.49503"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2009.12.006"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2019.00116"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R117.791962"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.12.065"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2019.241232"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.10.411"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.10308"},{"issue":"23","key":"e_1_2_9_27_1","first-page":"2691","article-title":"NCOA4 is regulated by HIF and mediates mobilization of murine hepatic iron stores after blood loss","volume":"136","author":"Li X","year":"2020","journal-title":"Blood"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/7727"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-04-1086"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3465"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0701-2"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11002-5"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.07.049"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.07.047"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2015.09.041"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1519473113"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.09.023"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2019.224899"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-10-808873"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1511701112"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.11.6709"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-05-850404"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/2211-5463.12573"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2462"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature14601"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0913192107"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1301764110"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan1078"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaz2193"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA119.009578"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-14004-5"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI127341"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1057206"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1038\/41343"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/35001596"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(00)80425-6"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/5979"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2010.08.003"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI38499"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2008.12.012"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.238667"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.03.007"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI122359"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA118.005549"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2011.07.014"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.10.413"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2015.05.002"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V30.4.417.417"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2014.07.007"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.4822"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1720739115"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-27107-8"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI90896"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2012.01779.x"},{"issue":"2","key":"e_1_2_9_75_1","first-page":"249","article-title":"Prevalence of endocrine complications and short stature in patients with thalassaemia major: a multicenter study by the Thalassaemia International Federation (TIF)","volume":"2","author":"De Sanctis V","year":"2004","journal-title":"Pediatr Endocrinol Rev"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2017.00804"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2017.04.036"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2014.00024"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.98867"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2009.04066.x"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.09.021"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2018.212977"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20140857"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6967622"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0089270"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-2061-8"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2014.10.029"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2005.01.003"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-01-330324"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.25746"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-04-842997"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aal2022"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1822010116"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2015.09.006"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2009.03.006"},{"issue":"12","key":"e_1_2_9_96_1","first-page":"1595","article-title":"Expression of alternative transcripts of ferroportin\u20101 during human erythroid differentiation","volume":"90","author":"Cianetti L","year":"2005","journal-title":"Haematologica"},{"key":"e_1_2_9_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2013.02.026"},{"key":"e_1_2_9_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2015.06.017"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-08-595256"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2012.12.016"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-03-492454"},{"key":"e_1_2_9_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2013.01.007"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-04-1365"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-12-4703"},{"key":"e_1_2_9_105_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0098072"},{"key":"e_1_2_9_106_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awz072"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1103786"},{"key":"e_1_2_9_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2007.10.006"},{"key":"e_1_2_9_109_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00860"},{"key":"e_1_2_9_110_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-06-2259"},{"key":"e_1_2_9_111_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aau6481"},{"key":"e_1_2_9_112_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1422373112"},{"key":"e_1_2_9_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.07.089"},{"key":"e_1_2_9_114_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.19804"},{"key":"e_1_2_9_115_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.034545"},{"key":"e_1_2_9_116_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.1.05729"},{"key":"e_1_2_9_117_1","doi-asserted-by":"publisher","DOI":"10.1677\/JOE-07-0528"},{"key":"e_1_2_9_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2019.10.005"},{"key":"e_1_2_9_119_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2010.033449"},{"key":"e_1_2_9_120_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24359"},{"key":"e_1_2_9_121_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C600197200"},{"key":"e_1_2_9_122_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.11.028"},{"key":"e_1_2_9_123_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24178"},{"key":"e_1_2_9_124_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0122696"},{"key":"e_1_2_9_125_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24547"},{"key":"e_1_2_9_126_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1777"},{"key":"e_1_2_9_127_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI25683"},{"key":"e_1_2_9_128_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-03-143354"},{"key":"e_1_2_9_129_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.335"},{"key":"e_1_2_9_130_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.320"},{"key":"e_1_2_9_131_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0060534"},{"key":"e_1_2_9_132_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-06-721571"},{"key":"e_1_2_9_133_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-07-729822"},{"key":"e_1_2_9_134_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.24888"},{"key":"e_1_2_9_135_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31048"},{"key":"e_1_2_9_136_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019002620"},{"key":"e_1_2_9_137_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.25366"},{"key":"e_1_2_9_138_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42255-019-0063-6"},{"key":"e_1_2_9_139_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2010.031963"},{"key":"e_1_2_9_140_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0084906"},{"issue":"10","key":"e_1_2_9_141_1","first-page":"241984","article-title":"Hemochromatosis proteins are dispensable for the acute hepcidin response to BMP2","volume":"105","author":"Pagani A","year":"2020","journal-title":"Haematologica"},{"key":"e_1_2_9_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2007.11.014"},{"key":"e_1_2_9_143_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28254"},{"key":"e_1_2_9_144_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-07-795658"},{"key":"e_1_2_9_145_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.4231"},{"key":"e_1_2_9_146_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06318-7"},{"key":"e_1_2_9_147_1","unstructured":"Besson\u2010FournierC MeynardD Canonne\u2010HergauxF Aguilar\u2010MartinezP RothM\u2010P CoppinH.Spatial zonation of hepcidin in the liver is patterned by testosterone.Eighth Congress of the International BioIron Society Heidelberg Germany.2019."},{"key":"e_1_2_9_148_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1244880"},{"key":"e_1_2_9_149_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12681"},{"key":"e_1_2_9_150_1","doi-asserted-by":"publisher","DOI":"10.1038\/sigtrans.2016.44"},{"key":"e_1_2_9_151_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13817"},{"key":"e_1_2_9_152_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI0215686"},{"key":"e_1_2_9_153_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-02-270322"},{"key":"e_1_2_9_154_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-06-028787"},{"key":"e_1_2_9_155_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-07-658419"},{"key":"e_1_2_9_156_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2996"},{"key":"e_1_2_9_157_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-06-584607"},{"key":"e_1_2_9_158_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2016.150227"},{"key":"e_1_2_9_159_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-11-681494"},{"key":"e_1_2_9_160_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-06-857995"},{"key":"e_1_2_9_161_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-014-2550-4"},{"key":"e_1_2_9_162_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-08-596254"},{"key":"e_1_2_9_163_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20170396"},{"key":"e_1_2_9_164_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-04-281360"},{"key":"e_1_2_9_165_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2073"},{"key":"e_1_2_9_166_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-07-2614"},{"key":"e_1_2_9_167_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2018.199810"},{"key":"e_1_2_9_168_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2017.187245"},{"key":"e_1_2_9_169_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2018893099"},{"key":"e_1_2_9_170_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI126645"},{"key":"e_1_2_9_171_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04446-8"},{"key":"e_1_2_9_172_1","doi-asserted-by":"publisher","DOI":"10.1093\/abbs\/gmt107"},{"key":"e_1_2_9_173_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.25615"},{"key":"e_1_2_9_174_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00105.2012"},{"key":"e_1_2_9_175_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3001127"},{"key":"e_1_2_9_176_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-3804"},{"key":"e_1_2_9_177_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-019-0406-1"},{"key":"e_1_2_9_178_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01479"},{"key":"e_1_2_9_179_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-08-663245"},{"key":"e_1_2_9_180_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-02-337212"},{"key":"e_1_2_9_181_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2015.06.025"},{"key":"e_1_2_9_182_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.01.069"},{"key":"e_1_2_9_183_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4146"},{"key":"e_1_2_9_184_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1150179"},{"key":"e_1_2_9_185_1","doi-asserted-by":"publisher","DOI":"10.2337\/db14-0646"},{"key":"e_1_2_9_186_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI44421"},{"key":"e_1_2_9_187_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI81860"},{"key":"e_1_2_9_188_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-11-737411"},{"key":"e_1_2_9_189_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI129382"},{"key":"e_1_2_9_190_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI66969"},{"key":"e_1_2_9_191_1","doi-asserted-by":"publisher","DOI":"10.1097\/HS9.0000000000000301"},{"key":"e_1_2_9_192_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019003140"},{"key":"e_1_2_9_193_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2019.01.003"},{"key":"e_1_2_9_194_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1804281"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.26001","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ajh.26001","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.26001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T02:08:39Z","timestamp":1693879719000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.26001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,13]]},"references-count":193,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/ajh.26001"],"URL":"https:\/\/doi.org\/10.1002\/ajh.26001","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,13]]},"assertion":[{"value":"2020-06-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}