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In a minority of patients, P\/LP variants related to primary immuno\u2010regulatory disorders were found. This new form may fit the group of \u201c<jats:italic>Likely acquired neutropenia,\u201d<\/jats:italic> a provisional category included in the recent International Guidelines on Diagnosis and Management of Neutropenia of EHA and EUNET INNOCHRON ACTION 18233. The early recognition of this form of neutropenia would help clinicians to delineate better specific monitoring plans, genetic counseling, and potentially targeted therapies.<\/jats:p>","DOI":"10.1002\/ajh.27221","type":"journal-article","created":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T08:48:47Z","timestamp":1706518127000},"page":"534-542","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Late\u2010onset and long\u2010lasting neutropenias in the young: A new entity anticipating immune\u2010dysregulation disorders"],"prefix":"10.1002","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7096-4580","authenticated-orcid":false,"given":"F.","family":"Fioredda","sequence":"first","affiliation":[{"name":"Haematology Unit\u2010IRCCS Istituto Giannina Gaslini  Genova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Beccaria","sequence":"additional","affiliation":[{"name":"Epidemiology and Biostatistics Unit and DOPO Clinic\u2010IRCCS Istituto Giannina Gaslini  Genova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Casartelli","sequence":"additional","affiliation":[{"name":"Haematology Unit\u2010IRCCS Istituto Giannina Gaslini  Genova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Turrini","sequence":"additional","affiliation":[{"name":"Unit of Pediatric and OncoHematology, Department of Mother and Child, Azienda Ospedaliera Universitaria  Parma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Contratto","sequence":"additional","affiliation":[{"name":"Haematology Unit\u2010IRCCS Istituto Giannina Gaslini  Genova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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