{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T12:51:12Z","timestamp":1793019072498,"version":"4.5.0"},"reference-count":66,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T00:00:00Z","timestamp":1734912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Community\u2010acquired respiratory viral infections (CARV) significantly impact patients with hematological malignancies (HM), leading to high morbidity and mortality. However, large\u2010scale, real\u2010world data on CARV in these patients is limited. This study analyzed data from the EPICOVIDEHA\u2010EPIFLUEHA registry, focusing on patients with HM diagnosed with CARV during the 2023\u20132024 autumn\u2013winter season. The study assessed epidemiology, clinical characteristics, risk factors, and outcomes. The study examined 1312 patients with HM diagnosed with CARV during the 2023\u20132024 autumn\u2013winter season. Of these, 59.5% required hospitalization, with 13.5% needing ICU admission. The overall mortality rate was 10.6%, varying by virus: parainfluenza (21.3%), influenza (8.8%), metapneumovirus (7.1%), RSV (5.9%), or SARS\u2010CoV\u20102 (5.0%). Poor outcomes were significantly associated with smoking history, severe lymphopenia, secondary bacterial infections, and ICU admission. This study highlights the severe risk CARV poses to patients with HM, especially those undergoing active treatment. The high rates of hospitalization and mortality stress the need for better prevention, early diagnosis, and targeted therapies. Given the severe outcomes with certain viruses like parainfluenza, tailored strategies are crucial to improving patient outcomes in future CARV seasons.<\/jats:p>","DOI":"10.1002\/ajh.27565","type":"journal-article","created":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T13:00:54Z","timestamp":1734958854000},"page":"358-374","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Respiratory Viruses in Patients With Hematological Malignancy in Boreal Autumn\/Winter 2023\u20132024: <scp>EPICOVIDEHA<\/scp>\u2010<scp>EPIFLUEHA<\/scp> Report"],"prefix":"10.1002","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6766-8297","authenticated-orcid":false,"given":"Jon","family":"Salmanton\u2010Garc\u00eda","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Cologne and University Hospital Cologne, Institute of Translational Research, Excellence Cluster on Cellular Stress Responses in 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