{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T16:16:11Z","timestamp":1770480971116,"version":"3.49.0"},"reference-count":8,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,11]],"date-time":"2006-07-11T00:00:00Z","timestamp":1152576000000},"content-version":"vor","delay-in-days":11149,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[1976,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>All human T lymphoblast cell lines have been derived from subjects with leukemia secondary to thymic lymphoblastic lymphoma, a T cell malignacy, suggesting that such lines represent established cultures of neoplastic T cells. Based on this observation, we prepared rabbit antisera to T cell line HSB\u20102, removed reactivity for histocompatibility antigens and normal T cells by absorption with autocthonous B cell line CCRF\u2010SB and normal thymocytes, and tested the absorbed antisera by complement\u2010dependent cytotoxicity against a panel of normal and malignant cells.<\/jats:p><jats:p>A representative antiserum reacted with all 4 T cell lines (mean cytotoxic index = 56) and with tumor cells from 4 patients with T cell lymphma (mean cytotoxic index = 50) but did not react with tumor cells from 6 patients with other types of leukemias (mean cytotoxic index = 2), with 3 B cell lines (mean cytotoxic index = 1), normal peripheral blood lymphocytes (mean cytotoxic index = 5), or normal thymocytes (mean cytotoxic index = 6). We conclude that appropriately absorbed antisera to human T cell lines detect T cell lymphoma tumor antigens.<\/jats:p>","DOI":"10.1002\/ajh.2830010206","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T04:47:11Z","timestamp":1172033231000},"page":"219-223","source":"Crossref","is-referenced-by-count":54,"title":["Identification of T cell lymphoma tumor antigens on human T cell lines"],"prefix":"10.1002","volume":"1","author":[{"given":"Joseph","family":"Kaplan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerel","family":"Tilton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Ward D.","family":"Peterson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/241095a0"},{"key":"e_1_2_1_3_2","first-page":"521","article-title":"Childhood lymphoblastic lymphoma, a cancer of Thymus\u2010derived lymphocytes","volume":"34","author":"Kaplan J","year":"1974","journal-title":"Cancer Res"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1182\/blood.V40.3.303.303","article-title":"Increased proportion of complement receptor lymphocytes in the peripheral blood of patients with chronic lymphocytic leukemia","volume":"40","author":"Pincus S","year":"1972","journal-title":"Blood"},{"key":"e_1_2_1_5_2","first-page":"891","article-title":"Rosette\u2010forming human lymphoid cell lines. 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Establishment and evidence of Thymic origin of Thymus\u2010derived lymphocytes","volume":"49","author":"Minowada J","year":"1973","journal-title":"J Nat Cancer Inst"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/251745a0"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.174.4014.1136"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1967.03120080053007"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.139.5.1070"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.2830010206","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.2830010206","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T03:54:43Z","timestamp":1699847683000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.2830010206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,1]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1976,1]]}},"alternative-id":["10.1002\/ajh.2830010206"],"URL":"https:\/\/doi.org\/10.1002\/ajh.2830010206","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,1]]}}}