{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T21:00:55Z","timestamp":1791320455135,"version":"4.3.1"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,11]],"date-time":"2006-07-11T00:00:00Z","timestamp":1152576000000},"content-version":"vor","delay-in-days":10418,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[1978,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The transfusion histories over a 33\u2010month period of 50 patients with sickle cell disease were reviewed to determine the frequency of alloimmunization to red cell antigens following transfusion in these patients. There were 30 females and 20 males, aged 19\u201049 years. Eighteen (36%) were immunized of which thirteen were females. Five of the patients have formed only one antibody so far, while the other 13 have formed two or more. Thirty\u2010six antibodies were identified: 16 against various Rh antigens, 12 anti\u2010Lewis, 5 anti\u2010Kell and one each of anti\u2010Jk<jats:sup>a<\/jats:sup>, \u2010Fy<jats:sup>a<\/jats:sup> and \u2010M. The immunized patients received, on the average, more transfusions although there was a considerable degree of overlap between the immunized and nonimmunized groups. An approach to the hemotherapy of patients with sickle cell disease (SCD) is discussed.<\/jats:p>","DOI":"10.1002\/ajh.2830050204","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T05:17:28Z","timestamp":1172035048000},"page":"101-106","source":"Crossref","is-referenced-by-count":107,"title":["Post\u2010transfusion alloimmunization in patients with sickle cell disease"],"prefix":"10.1002","volume":"5","author":[{"given":"Armando R.","family":"Orlina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phyllis 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