{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T05:15:56Z","timestamp":1699852556775},"reference-count":8,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,7,11]],"date-time":"2006-07-11T00:00:00Z","timestamp":1152576000000},"content-version":"vor","delay-in-days":9567,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[1980,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Diarrhea with fever was a significant complaint in 26 of 280 (9.3%) of non\u2010SS children with S. pneumoniae bacteremia and four of 30 (13%) children with sickle syndromes and S. pneumoniae bacteremia. Two additional children with sickle\u2010cell disease and S. pneumoniae bacteremia developed diarrhea within hours of hospital admission; four of the six died. The mortality rate among 24 additional SS patients with S. pneumoniae bacteremia without diarrhea was 12.5% (3\/24). Only one of 26 non\u2010SS patients with diarrhea and S. penumoniae bacteremia died; she was surgically asplenic and had fulminant 9\u2010hour course. The seasonality of the diarrhea cases was similar to our overall experience, and the serotypes associated with the diarrhea cases were also representative of our overall experience. Although predominantly seen in infants, the oldest non\u2010SS patient was 12 years, and the oldest SS patient was nine years.<\/jats:p>","DOI":"10.1002\/ajh.2830080309","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T05:41:10Z","timestamp":1172036470000},"page":"309-314","source":"Crossref","is-referenced-by-count":3,"title":["Diarrhea in streptococcus pneumoniae bacteremia"],"prefix":"10.1002","volume":"8","author":[{"given":"Ruth Andrea","family":"Seeler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norman M.","family":"Jacobs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(77)80799-3"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1542\/peds.64.3.296","article-title":"Pneumococcal bacteremia in infants and children","volume":"64","author":"Jacobs NM","year":"1979","journal-title":"Pediatrics"},{"key":"e_1_2_1_4_2","first-page":"1","volume-title":"Brenneman's Practice of Pediatrics","author":"Darrow DC","year":"1964"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0022-3476(75)80159-4","article-title":"Pneumococcal septicemia and meningitis in the neonate","volume":"86","author":"Rhodes PG","journal-title":"J Pediatr"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.219.13.1763"},{"key":"e_1_2_1_7_2","first-page":"12","article-title":"Diplococcus pneumoniae","volume":"119","author":"Heldrich FJ","year":"1970","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_8_2","first-page":"336","article-title":"Occult pneumococcal bacteremia","volume":"119","author":"Torphy DE","year":"1970","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_9_2","first-page":"132","article-title":"Coincidental viral infection in the pathogenesis of postsplenectomy sepsis","volume":"52","author":"Dearth JC","year":"1978","journal-title":"Blood"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.2830080309","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.2830080309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T04:38:40Z","timestamp":1699850320000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.2830080309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,5]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1980,5]]}},"alternative-id":["10.1002\/ajh.2830080309"],"URL":"https:\/\/doi.org\/10.1002\/ajh.2830080309","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,5]]}}}