{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T19:54:13Z","timestamp":1759694053865},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,7,11]],"date-time":"2006-07-11T00:00:00Z","timestamp":1152576000000},"content-version":"vor","delay-in-days":8837,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[1982,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A family is described in which three of seven siblings developed a T\u2010cell lymphoblastic lymphoma. Tumor cells formed rosettes with sheep erythrocytes, lacked surface Ig, and expressed human T\u2010 but not B\u2010lymphocyte antigens. They lacked the enzyme terminal transferase suggesting a lymph node rather than thymic T\u2010cell origin. Autopsy findings supported this conclusion. All three sibs, like their father, had numerous cafe'\u2010au'lait spots indicative of Von Recklinghausen neurofibromatosis. One child had a subcutaneous fibroma, and another had multiple colonic polyps and exostoses characteristic of Gardner syndrome. Both are autosomal dominant conditions known to predispose to malignancies. The genetic factors responsible for these conditions may also predispose to the development of \u201cpostthymic\u201d T\u2010cell lymphoblastic lymphoma.<\/jats:p>","DOI":"10.1002\/ajh.2830120306","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T07:37:43Z","timestamp":1172043463000},"page":"247-250","source":"Crossref","is-referenced-by-count":17,"title":["Familial T\u2010cell lymphoblastic lymphoma: Association with von recklinghausen neurofibromatosis and gardner syndrome"],"prefix":"10.1002","volume":"12","author":[{"given":"Joseph","family":"Kaplan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Cushing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung\u2010Ho","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"Poland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"Roscamp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene","family":"Perrin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirmala","family":"Bhaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,11]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"203","article-title":"Deaths from childhood leukemia and solid tumors among twins and other sibs in the United States","volume":"46","author":"Miller RW","year":"1971","journal-title":"J Nat Cancer Inst"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197410)34:4<1098::AID-CNCR2820340420>3.0.CO;2-L"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.197.1.25"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1182\/blood.V49.3.371.371","article-title":"T and B lymphocyte antigen\u2010positive null cell leukemias","volume":"49","author":"Kaplan J","year":"1977","journal-title":"Blood"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1977.tb00644.x"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197504102921504"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(70)80472-3"},{"key":"e_1_2_1_9_2","first-page":"376","article-title":"Follow\u2010up study of a family group exhibiting dominant inheritance for a syndrome including intestinal polyps, osteomas, fibromas and epidermal cysts","volume":"14","author":"Gardner EJ","year":"1962","journal-title":"Am J Human Genet"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197706)39:6<2633::AID-CNCR2820390649>3.0.CO;2-E"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197404)33:4<1134::AID-CNCR2820330437>3.0.CO;2-7"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.2830120306","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.2830120306","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T02:43:41Z","timestamp":1699843421000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.2830120306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,5]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1982,5]]}},"alternative-id":["10.1002\/ajh.2830120306"],"URL":"https:\/\/doi.org\/10.1002\/ajh.2830120306","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,5]]}}}