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We summarize the clinical and hematological features of 19 published cases from Western countries, in addition to a new case we encountered. The leukemic cells display characteristic morphological features and a T<jats:sub>3<\/jats:sub><jats:sup>+<\/jats:sup> T<jats:sub>4<\/jats:sub><jats:sup>+<\/jats:sup> T<jats:sub>8<\/jats:sub><jats:sup>\u2212<\/jats:sup> T<jats:sub>6<\/jats:sub><jats:sup>\u2212<\/jats:sup> surface antigenic phenotype. Overall survival is of short duration, but remission could be obtained in our case despite a subsequent relapse in skin and CNS. Geographic clusters of ATLL cases have led to the discovery of the possible role of a new retrovirus, HTLV, in the genesis of this rare malignancy.<\/jats:p>","DOI":"10.1002\/ajh.2830150413","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T09:44:32Z","timestamp":1172051072000},"page":"403-411","source":"Crossref","is-referenced-by-count":4,"title":["Adult T\u2010cell lymphoma leukemia in western countries"],"prefix":"10.1002","volume":"15","author":[{"given":"Jean Pierre","family":"Farcet","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathieu","family":"Kuentz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chantal","family":"Andre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Marc","family":"Darves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F\u00e9lix","family":"Reyes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Dreyfus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henri","family":"Rochant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197308162890703"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)93135-8"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197410)34:8 <1488::AID-CNCR2820340822>3.0.CO;2-C"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5920.643"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197504172921604"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(75)92127-3"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-83-4-534"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197808)42:2 <911::AID-CNCR2820420713>3.0.CO;2-G"},{"key":"e_1_2_1_10_2","first-page":"461","article-title":"A morphologic and immunologic surface marker study of 299 cases of non Hodgkin lymphomas and related leukemias","volume":"90","author":"Lukes RJ","year":"1978","journal-title":"Am J Pathol"},{"key":"e_1_2_1_11_2","first-page":"451","article-title":"Surface markers in leukemias and lymphomas","volume":"90","author":"Siegal FP","year":"1978","journal-title":"Am J Pathol"},{"key":"e_1_2_1_12_2","first-page":"699","article-title":"Results of multiparameters studies of T cell lymphoid neoplasms","volume":"72","author":"Collins RD","year":"1979","journal-title":"Am J Clin Pathol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1182\/blood.V56.6.1120.1120","article-title":"Immunologic classification of ALL. 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