{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T05:40:02Z","timestamp":1697866802845},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,11]],"date-time":"2006-07-11T00:00:00Z","timestamp":1152576000000},"content-version":"vor","delay-in-days":7741,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[1985,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 25\u2010yr\u2010old Japanese male showed unique T\u03b3 cell proliferation different from cases reported previously. His clinical and hematological features were characterized by persistent high fever and the appearance of large lymphocytes with abundant cytoplasm and azurophilic granules in the peripheral blood (11% of the leukocyte differential count) and the ascitic fluid. These lymphocytes showed the ability to bind the Fe portion of IgG and they beared the antigen of cytotoxic\/suppressor T\u2010cell defined by monoclonal antibodies. T\u2010cells from this patient suppressed the immunoglobulin production of normal B\u2010cells by pokeweed mitogen, although a polyclonal hypergammaglobulinemia was observed in the serum. Chromosomal abnormality indicated the malignant nature of the proliferating T\u03b3 cells in this patient. The clinical, hematological, and immunological findings characterized the disease of this patient as a distinct entity among the lymphoproliferative disorders of T\u2010cell origin.<\/jats:p>","DOI":"10.1002\/ajh.2830190111","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T09:59:51Z","timestamp":1172051991000},"page":"85-93","source":"Crossref","is-referenced-by-count":3,"title":["A lymphoproliferative disorder of T\u03b3 cells with the phenotype of cytotoxic suppressor T\u2010cell"],"prefix":"10.1002","volume":"19","author":[{"given":"Tatsuhiko","family":"Amagasaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junji","family":"Shibata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiichi","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Nishino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuaki","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Sadamori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masao","family":"Tomonaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichiro","family":"Kinoshita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michito","family":"Ichimaru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.146.1.184"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1182\/blood.V60.1.1.1","article-title":"Surface markers on leukemia and lymphoma cells: Recent advances","volume":"60","author":"Foon KA","year":"1982","journal-title":"Blood"},{"key":"e_1_2_1_4_2","first-page":"3","article-title":"Immunologic studies of chronic lymphocytic leukemia and non\u2014Hodgin's lymphoma in Nagasaki district","volume":"9","author":"Kamihira S","year":"1979","journal-title":"Jpn J Clin Oncol"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830060812"},{"key":"e_1_2_1_6_2","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1182\/blood.V61.1.192.192","article-title":"Phenotypic and functional analysis of leukemic cells from 16 patients with adult T\u2014cell leukemia\/lymphoma","volume":"61","author":"Yamada Y","year":"1983","journal-title":"Blood"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/newbio232031a0"},{"key":"e_1_2_1_8_2","first-page":"337","article-title":"T\u2013cell malignant lymphoma in Nagasaki district and its problems","volume":"9","author":"Ichimaru M","year":"1979","journal-title":"Jpn J Clin Oncol"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19821015)50:8<1554::AID-CNCR2820500815>3.0.CO;2-Q"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1182\/blood.V50.3.481.481","article-title":"Adult T\u2014cell leukemia: Clinical and hematologic features of 16 cases","volume":"50","author":"Uchiyama T","year":"1977","journal-title":"Blood"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00320691"},{"key":"e_1_2_1_12_2","first-page":"59","article-title":"Ultrastructural studies of parallel tubular arrays in human lymphocytes","volume":"78","author":"Brunning RD","year":"1975","journal-title":"Am J Pathol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1182\/blood.V56.4.653.653","article-title":"Characterization of a suppressor T\u2014cell chronic lymphocytic leukemia with ADCC but not NK activity","volume":"56","author":"Pandolfi F","year":"1980","journal-title":"Blood"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198004243021702"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00919136"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(77)90422-3"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(75)92127-3"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197911)44:5<1652::AID-CNCR2820440518>3.0.CO;2-D"},{"key":"e_1_2_1_19_2","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1182\/blood.V57.6.1025.1025","article-title":"Pure red cell aplasia and hypogammaglobulinemia associated with T\u2014y cell chronic lymphocytic leukemia","volume":"57","author":"Nagasawa T","year":"1981","journal-title":"Blood"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0145-2126(81)90001-1"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(82)90004-6"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19830415)51:8<1434::AID-CNCR2820510818>3.0.CO;2-4"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0145-2126(80)90028-4"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01711277"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198103123041106"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(81)80078-0"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.2830190111","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.2830190111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T15:43:51Z","timestamp":1697816631000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.2830190111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,5]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1985,5]]}},"alternative-id":["10.1002\/ajh.2830190111"],"URL":"https:\/\/doi.org\/10.1002\/ajh.2830190111","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,5]]}}}