{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T22:14:58Z","timestamp":1785190498429,"version":"3.55.0"},"reference-count":8,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,11]],"date-time":"2006-07-11T00:00:00Z","timestamp":1152576000000},"content-version":"vor","delay-in-days":6766,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[1988,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The benefit of oxygen (O<jats:sub>2<\/jats:sub>) therapy in non\u2010hypoxic sickle cell patients in painful crisis is uncertain. We report a case of a non\u2010hypoxic sickle cell patient in painful crisis who developed marrow red cell hypoplasia requiring transfusion support after O<jats:sub>2<\/jats:sub> therapy. The uncertain benefits of O<jats:sub>2<\/jats:sub> use in such cases must be weighed against the serious and underrecognized risks of transfusion. In patients who develop O<jats:sub>2<\/jats:sub>\u2010induced marrow red cell hypoplasia, cessation of O<jats:sub>2<\/jats:sub> therapy may reverse the anemia and obviate the need for transfusion.<\/jats:p>","DOI":"10.1002\/ajh.2830270117","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T10:52:31Z","timestamp":1172055151000},"page":"67-68","source":"Crossref","is-referenced-by-count":10,"title":["Oxygen\u2010induced marrow red cell hypoplasia leading to transfusion in sickle painful crisis"],"prefix":"10.1002","volume":"27","author":[{"given":"Philip K.","family":"Lane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen H.","family":"Embury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pearl T. C. Y.","family":"Toy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(16)31115-4"},{"key":"e_1_2_1_3_2","first-page":"585","volume-title":"Hematology","author":"Beutler E","year":"1983"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.133.4.698"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.me.32.020181.001211"},{"issue":"2","key":"e_1_2_1_6_2","first-page":"1082","article-title":"A simple and rapid method for demonstrating sickling of the red blood cells: The use of reducing agents","volume":"33","author":"Daland GA","year":"1948","journal-title":"J Lab Clin Med"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V41.5.653.653"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI101539"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198408023110504"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.2830270117","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.2830270117","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T23:38:05Z","timestamp":1697845085000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.2830270117"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1988,1]]}},"alternative-id":["10.1002\/ajh.2830270117"],"URL":"https:\/\/doi.org\/10.1002\/ajh.2830270117","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,1]]}}}