{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T23:13:58Z","timestamp":1763507638602},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,11]],"date-time":"2006-07-11T00:00:00Z","timestamp":1152576000000},"content-version":"vor","delay-in-days":6369,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[1989,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We assessed the risk of human immunodeficiency virus (HIV) transmission from heterosexual seropositive hemophilic men to their female sex partners through an HIV sero\u2010survey and questionnaire study conducted during 1984\u20131987. Five percent of 21 female partners of asymptomatic men and 11% of 35 partners of HIV\u2010symptomatic (acquired immunodeficiency syndrome [AIDS], AIDS\u2010related complex [ARC], peripheral generalized lymphadenopathy [PGL]) hemophilic men had been infected when first tested. One of 19 seronegative women tested about 1 year later reportedly seroconverted. Only 18% of a sample of the serosurvey women responding to sex practices questions said their partners used condoms \u201cnearly always.\u201d Over 60% engaged in oral\/genital sex in addition to vaginal intercourse. Only 12% of still\u2010seronegative women followed the preventive strategy of consistent avoidance of oral\/genital sex, together with consistent condom use by the male partner.<\/jats:p><jats:p>Further evidence for heterosexual transmission comes from the CDC national AIDS surveillance reports showing 25 women who acquired HIV infection through heterosexual contact with U.S. hemophilic men (September 6, 1988). Seven (28%) were diagnosed and reported in the first 6 months of 1988. Their ages range from 20 years to more than 70 years. The dates of infection for the women are unknown but must have been at least 5 years before AIDS diagnosis for at least one. Only approximately 30% of their male partners had already manifested any HIV\u2010assodaied illness.<\/jats:p><jats:p>Through May 18, 1988, six cases of AIDS have occurred in children whose infection was acquired through exposure of the mother to a hemophific partner. Four were diagnosed in latter 1987. The median age at diagnosis was 4.5 months. Four had died. None of their mothers is as yet diagnosed.<\/jats:p>","DOI":"10.1002\/ajh.2830300204","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T11:49:28Z","timestamp":1172058568000},"page":"68-76","source":"Crossref","is-referenced-by-count":16,"title":["Sex practice correlates of human immunodeficiency virus transmission and acquired immunodeficiency syndrome incidence in heterosexual partners and offspring of U.S. hemophilic men"],"prefix":"10.1002","volume":"30","author":[{"given":"Dale N.","family":"Lawrence","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janine M.","family":"Jason","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert C.","family":"Holman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peggy","family":"Heine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce L.","family":"Evatt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-100-1-62"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-100-6-915_3"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)91904-X"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-102-5-623"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.291.6497.695"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365548609021653"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198608213150815"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1986.tb05558.x"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1055\/s-0038-1661462","article-title":"Conjugal transmission of HTLV\u2010III and lymphadenopathy in Christmas disease","volume":"55","author":"Andes WA","year":"1986","journal-title":"Thromb Haemost"},{"key":"e_1_2_1_11_2","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1001\/jama.1986.03370020058027","article-title":"HTLV\u2010III\/LAV antibody and immune status of household contacts and sexual partners of persons with hemophilia","volume":"255","author":"Jason JM","year":"1986","journal-title":"JAMA"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.255.13.1702b"},{"key":"e_1_2_1_13_2","unstructured":"OperskalskiE and theTransfusion Safety Study Group: Transmission of human immunodeficiency virus infection to household contacts of persons with congenital hematologic disorders [Abstract]. Program of the 28th Annual Meeting American Society of Hematology Dec 6\u20139 1986 San Francisco: 131A."},{"key":"e_1_2_1_14_2","first-page":"593","article-title":"HIV infection and pregnancies in sexual partners of HIV\u2010seropositive hemophilic men\u2014United States","volume":"36","author":"Centers for Disease Control","year":"1987","journal-title":"MMWR"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.1987.3.355"},{"key":"e_1_2_1_16_2","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1001\/jama.1987.03400060064030","article-title":"Male\u2010to\u2010female transmission of human immunodeficiency virus","volume":"258","author":"Padian N","year":"1987","journal-title":"JAMA"},{"key":"e_1_2_1_17_2","first-page":"54","article-title":"Human immunodeficiency virus (HIV) transmission in female sexual partners of HIV antibody positive hemophiliacs","volume":"103","author":"Ragni MV","year":"1988","journal-title":"Public Health Rep"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.148.6.1299"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830280106"},{"key":"e_1_2_1_20_2","unstructured":"KamradtT NieseD SchneweisKE BrackmannHH KampsBS:Heterosexual transmission of HIV in hemophiliacs. Abstr 4008 IV International Conference on AIDS June 12\u201316 1988 Stockholm."},{"key":"e_1_2_1_21_2","unstructured":"TsangVCW HancockK WilsonM PalmerDF WhakySD McDougalJS KennedyS: \u201cEnzyme\u2010Linked Immunoelectrotransfer Blot Technique (Western blot) for Human T\u2010Lymphotropic Virus Type III\/Lymphadenopathy\u2010Associated Virus (HTLV\u2010III\/LAV) Antibodies.\u201d Atlanta: Centers for Disease Control 1986(Immunology series no. 15 procedural guide)."},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0010-4809(75)90048-8"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1977.10479909"},{"key":"e_1_2_1_24_2","first-page":"13","volume-title":"Statistical Methods for Rates and Proportions","author":"Fleiss JL","year":"1981"},{"key":"e_1_2_1_25_2","first-page":"23","volume-title":"Nonparametrics\u2014Statistical Methods Based on Ranks","author":"Lehmann EL","year":"1975"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1988.03720010033036"},{"key":"e_1_2_1_27_2","first-page":"101","article-title":"Prevention of acquired immune deficiency syndrome (AIDS)","volume":"32","author":"Centers for Disease Control","year":"1983","journal-title":"MMWR"},{"key":"e_1_2_1_28_2","volume-title":"AIDS Update: Hemophilia and Acquired Immune Deficiency Syndrome (AIDS): Intimacy and Sexual Behavior","author":"National Hemophilia Foundation","year":"1985"},{"key":"e_1_2_1_29_2","first-page":"721","article-title":"Recommendations for assisting in the prevention of perinatal transmission of human T\u2010lymphotropic virus type III\/lymphadenopathy\u2010associated virus and acquired immunodeficiency syndrome","volume":"34","author":"Centers for Disease Control","year":"1985","journal-title":"MMWR"},{"key":"e_1_2_1_30_2","first-page":"133","article-title":"Condoms for prevention of sexually transmitted diseases","volume":"37","author":"Centers for Disease Control","year":"1988","journal-title":"MMWR"},{"key":"e_1_2_1_31_2","first-page":"152","article-title":"Additional recommendations to reduce sexual and drug abuse\u2010related transmission of human T\u2010lymphotropic virus type III\/lymphadenopathy\u2010associated virus","volume":"35","author":"Centers for Disease Control","year":"1986","journal-title":"MMWR"},{"key":"e_1_2_1_32_2","volume-title":"Hemophilia Information Exchange: Intimacy, Sexuality and Hemophilia","author":"National Hemophilia Foundation","year":"1987"},{"key":"e_1_2_1_33_2","volume-title":"Safer Sex: Guidelines for the Prevention of Transmission of the AIDS Virus","author":"Waterbury","year":"1987"},{"key":"e_1_2_1_34_2","volume-title":"What Women Should Know About HIV Infection AIDS and Hemophilia","author":"Nimorwicz P","year":"1988"},{"key":"e_1_2_1_35_2","volume-title":"Let's Talk About Sex","author":"Levine SB","year":"1988"},{"key":"e_1_2_1_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830260202"},{"key":"e_1_2_1_37_2","unstructured":"WassermanK WilsonPA. Psychosocial impact of AIDS. 19A Abstracts of the 39th Annual meeting of the National Hemophilia Foundation Omaha NE October 9\u201310 1987."},{"key":"e_1_2_1_38_2","unstructured":"National Center for Health Statistics Dawson DA Cynamon M Fitti JE: AIDS knowledge and attitudes for October1987. Provisional data from the National Health Interview Survey. Advance Data from Vital and Health Statistics. No. 150. DHHS Pub. No. (PHS) 88\u20131250. Public Health Service. Hyattsville MD."}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.2830300204","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.2830300204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T01:55:16Z","timestamp":1697939716000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.2830300204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,2]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1989,2]]}},"alternative-id":["10.1002\/ajh.2830300204"],"URL":"https:\/\/doi.org\/10.1002\/ajh.2830300204","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,2]]}}}