{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T22:49:16Z","timestamp":1726094956506},"reference-count":5,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,11]],"date-time":"2006-07-11T00:00:00Z","timestamp":1152576000000},"content-version":"vor","delay-in-days":5701,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[1990,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We describe a patient with the lupus anti\u2010coagulant who had recurrent episodes, over a 2 year period, of a severe and disseminated intravascular coagulopathy. This patient also had positive serological assays for syphilis and anti\u2010cardiolipin antibodies. Associated with the coagulopathy were co\u2010expressed episodes of liver disease, ultimately terminating in fulminant liver failure. At autopsy the features were characteristic of the Budd\u2010Chiari syndrome. This is the first report to document how consumptive coagulopathy may present as a dominant feature of the anti\u2010phospholipid syndrome. It also clearly describes an immune mediated thrombotic mechanism as a cause of hepatic veno\u2010occlusive disorders. Furthermore, this case highlights the varied clinical spectrum of the anti\u2010phospholipid syndrome and suggests that a high index of suspicion is required to ensure its diagnosis.<\/jats:p>","DOI":"10.1002\/ajh.2830350413","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T12:10:34Z","timestamp":1172059834000},"page":"281-282","source":"Crossref","is-referenced-by-count":12,"title":["Recurrent disseminated intravascular coagulation and fulminant intra hepatic thrombosis in a patient with the anti\u2010phospholipid syndrome"],"prefix":"10.1002","volume":"35","author":[{"given":"J.","family":"Stinson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Tomkin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Harrison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Murray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Feighery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0307-742X(21)00606-8","article-title":"Anti\u2013phospholipid antibodies","volume":"11","author":"Harris EN","year":"1985","journal-title":"Clin Rheum Dis"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.48.5.362"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.62.734.1081"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.48.5.355"},{"key":"e_1_2_1_6_2","first-page":"3271","volume-title":"Gastroenterology.","author":"Bolt RJ","year":"1985"}],"container-title":["American Journal of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajh.2830350413","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajh.2830350413","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T16:41:29Z","timestamp":1697992889000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajh.2830350413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,12]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1990,12]]}},"alternative-id":["10.1002\/ajh.2830350413"],"URL":"https:\/\/doi.org\/10.1002\/ajh.2830350413","archive":["Portico"],"relation":{},"ISSN":["0361-8609","1096-8652"],"issn-type":[{"value":"0361-8609","type":"print"},{"value":"1096-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,12]]}}}