{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T09:33:01Z","timestamp":1792315981927,"version":"4.4.0"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,11]],"date-time":"2006-07-11T00:00:00Z","timestamp":1152576000000},"content-version":"vor","delay-in-days":4484,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hematol"],"published-print":{"date-parts":[[1994,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 31\u2010year\u2010old woman presented with fever and arthralgla. Despite treatment with antimicrobials and cortlcosteroids, her symptoms persisted. A diagnosis of myelodysplastic syndrome (MDS)\u2010refractory anemia (RA) was made by pancytopenia, dysplasia, and trisomy 8. Cultures of bone marrow, blood, and gastric juice showed Mycobacterium aviumintraceliuiare (MAI). She was treated with antimycobacterial drugs and recombinant human G\u2010CSF\/M\u2010CSF and showed an initial response, but spike fever recurred and pancytopenia progressed. Hepatospienomegaly and marked retroperitoneal lymphade\u2010nopathy were revealed, indicating further dissemination of MAI. Treatment with recombinant human GM\u2010CSF and very\u2010low\u2010dose cytosine arabinoside, was started but was not effective. This case showed significant reduction in peripheral blood 1\u2010lymphocytes, especially the CD4<jats:sup>+<\/jats:sup> population, and low immunoglobulin levels. immunodeficiency state associated with long\u2010term steroid therapy and MDS seemed to contribute to the development of the disseminated infection with MAI. \u00a9 1994 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajh.2830450410","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T13:47:32Z","timestamp":1172065652000},"page":"325-329","source":"Crossref","is-referenced-by-count":11,"title":["Disseminated mycobacterium <i>avium<\/i>\u2010intracellulare infection in a patient with myelodysplastic syndrome (refractory anemia)"],"prefix":"10.1002","volume":"45","author":[{"given":"Hiroko","family":"Tsukada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takaaki","family":"Chou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Ishizuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Ogawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takako","family":"Saeki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Wakabayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaaki","family":"Arakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.93.5.926"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/139.1.4"},{"key":"e_1_2_1_4_2","first-page":"572","article-title":"Disseminated 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