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Similarly to myeloma and lymphoma, any\u2010grade CRS was very common at a pooled rate of 85% and any\u2010grade infections occurred at a pooled rate of 29%. Apart from grade \u2265\u20093 neutropenia (70%), grade \u2265\u20093 anemia emerged as an equally common serious hematological AE (69%). In conclusion, CAR T\u2010cells constitute a highly effective therapeutic option for patients with hematological cancer at relapse, but close patient monitoring is essential to address treatment\u2010related toxicities.<\/jats:p>","DOI":"10.1002\/ajh.70201","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T12:00:56Z","timestamp":1767960056000},"page":"497-511","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Chimeric Antigen Receptor T\u2010Cells (\n                    <scp>CAR<\/scp>\n                    T\u2010Cells) in Hematological Malignancies: A Systematic Review and Meta\u2010Analysis of Proportions From Clinical Trials"],"prefix":"10.1002","volume":"101","author":[{"given":"Charalampos","family":"Filippatos","sequence":"first","affiliation":[{"name":"Department of Clinical Therapeutics Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens  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