{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T07:37:11Z","timestamp":1777534631674,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,4,30]],"date-time":"2009-04-30T00:00:00Z","timestamp":1241049600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hum Biol"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This commentary links early pregnancy milestones (rescue of the corpus luteum, the luteal\u2010placental shift, and blocking of the spiral arteries) with the pattern of gestation\u2010specific pregnancy loss in humans. The objective is to describe the pattern and present an adaptive hypothesis: that high first trimester pregnancy loss results from selection to reduce the risk of maternal morbidity and mortality associated with human delivery. Specific questions within the broad framework of this hypothesis can be addressed with research in comparative physiology and endocrinology. Am. J. Hum. Biol., 2009. Published 2009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ajhb.20935","type":"journal-article","created":{"date-parts":[[2009,4,30]],"date-time":"2009-04-30T15:40:53Z","timestamp":1241106053000},"page":"725-727","source":"Crossref","is-referenced-by-count":19,"title":["The gestational timing of pregnancy loss: Adaptive strategy?"],"prefix":"10.1002","volume":"21","author":[{"given":"Donna Day","family":"Baird","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,4,30]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-012288145-9\/50014-0"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.102.008425"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsgi.2004.03.003"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-197802000-00001"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199101000-00006"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1991.tb37914.x"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719107309588"},{"key":"e_1_2_1_9_1","series-title":"The physiology of reproduction","first-page":"1995","author":"Hodgen GD","year":"1988"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7292(85)90074-8"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dml016"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68397-9"},{"key":"e_1_2_1_13_1","first-page":"433","volume-title":"Conception to Birth","author":"Kline J","year":"1989"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a004085"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1272\/jnms.70.250"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-0528.2002.00010.x"},{"key":"e_1_2_1_17_1","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/S0015-0282(16)55032-8","article-title":"Corpus luteum function in successful in vitro fertilization cycles","volume":"57","author":"Shamma FN","year":"1992","journal-title":"Fertil Steril"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra061360"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(73)90057-4"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198807283190401"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199906103402304"}],"container-title":["American Journal of Human Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajhb.20935","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajhb.20935","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T10:18:11Z","timestamp":1700043491000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajhb.20935"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,30]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["10.1002\/ajhb.20935"],"URL":"https:\/\/doi.org\/10.1002\/ajhb.20935","archive":["Portico"],"relation":{},"ISSN":["1042-0533","1520-6300"],"issn-type":[{"value":"1042-0533","type":"print"},{"value":"1520-6300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,30]]}}}