{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T00:09:57Z","timestamp":1716854997859},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,6,7]],"date-time":"2014-06-07T00:00:00Z","timestamp":1402099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hum Biol"],"published-print":{"date-parts":[[2014,9,10]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The causal role of some cardiovascular risk factors, such as HDL cholesterol, has been increasingly challenged and attention is returning to all elements of Virchow's triad, i.e., hypercoagulability (including viscosity) as well as endothelial function and blood flow. We examined the life course origins of coagulability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We used multivariable linear regression to assess whether childhood influences, proxied by height and its components, were associated with hematocrit (Hct), hemoglobin (HGB), and other hematological parameters in 28,595 older Chinese adults (mean age\u2009=\u200961.8 years) from the Guangzhou Biobank Cohort Study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Adjusted for age, sex, and recruitment phase, leg length was negatively associated with platelets (PLT) (\u22120.83 \u00d7 10<jats:sup>9<\/jats:sup>\/l per centimeter (cm), 95% confidence interval (CI) \u22121.01 to \u22120.65). Sitting height and height were positively associated with Hct (0.05% per cm, 95% CI 0.04\u20130.07 for sitting height; 0.02% per cm, 95% CI 0.01\u20130.02 for height), HGB (0.21 g\/l per cm, 95% CI 0.17\u20130.25; 0.07 g\/l per cm, 95% CI 0.04\u20130.09) and negatively associated with PLT (\u22121.2 \u00d7 10<jats:sup>9<\/jats:sup>\/l per cm, 95% CI \u22121.4 to \u22121.0; \u22120.83 \u00d7 10<jats:sup>9<\/jats:sup>\/l per cm, 95% CI \u22120.95 to \u22120.70). Further adjustment for potential confounders did little to change the estimates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>For the first time we provide anthropometric evidence for the different roles of prepubertal and pubertal influences in relation to Hct and HGB. Whether factors that promote leg growth but reduce growth of sitting height may help to prevent cardiovascular events, via effects on hypercoagulability or viscosity, overall or in specific subgroups, remains to be determined. Am. J. Hum. Biol. 26:603\u2013608, 2014. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajhb.22568","type":"journal-article","created":{"date-parts":[[2014,6,7]],"date-time":"2014-06-07T05:02:52Z","timestamp":1402117372000},"page":"603-608","source":"Crossref","is-referenced-by-count":1,"title":["Height, its components, and coagulability among older<scp>Chinese<\/scp>: The<scp>Guangzhou<\/scp>biobank cohort study"],"prefix":"10.1002","volume":"26","author":[{"given":"Y.","family":"Zhong","sequence":"first","affiliation":[{"name":"School of Public Health Li Ka Shing Faculty of Medicine, The University of Hong Kong Hong Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.Q.","family":"Jiang","sequence":"additional","affiliation":[{"name":"Guangzhou No. 12 Hospital Guangzhou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.K.","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Public Health and Epidemiology University of Birmingham Birmingham United Kingom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.S.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Guangzhou No. 12 Hospital Guangzhou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Liu","sequence":"additional","affiliation":[{"name":"Guangzhou No. 12 Hospital Guangzhou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.L.","family":"Jin","sequence":"additional","affiliation":[{"name":"Guangzhou No. 12 Hospital Guangzhou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.H.","family":"Lam","sequence":"additional","affiliation":[{"name":"School of Public Health Li Ka Shing Faculty of Medicine, The University of Hong Kong Hong Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.M.","family":"Leung","sequence":"additional","affiliation":[{"name":"School of Public Health Li Ka Shing Faculty of Medicine, The University of Hong Kong Hong Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.M.","family":"Schooling","sequence":"additional","affiliation":[{"name":"School of Public Health Li Ka Shing Faculty of Medicine, The University of Hong Kong Hong Kong SAR China"},{"name":"CUNY School of Public Health and Hunter College New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,6,7]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"855","article-title":"Collected anthropometric data on the Chinese","volume":"39","author":"PH S","journal-title":"China Med J"},{"key":"e_1_2_6_3_1","first-page":"vi + 55","volume-title":"Global atlas on cardiovascular disease prevention and control","author":"Mendis S","year":"2011"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03344122"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199808273390903"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d4169"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajhb.21016"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.287.6390.449"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2012.76"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/09537104.2010.494743"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.22116"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-2575"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq030"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.57.2.141"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.52.3.142"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/advan.00099.2006"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000097694"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyl131"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.84.10.3613"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-5922.2010.00197.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2004.025387"},{"key":"e_1_2_6_22_1","first-page":"CR387","article-title":"Could mean platelet volume be a predictive marker for acute myocardial infarction?","volume":"11","author":"Kilicli\u2010Camur N","year":"2005","journal-title":"Med Sci Monit Int Med J Exp Clin Res"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-002-0887-5"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.019950"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.21.2591"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-36771"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61728-0"},{"key":"e_1_2_6_28_1","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.3760\/cma.j.issn.0366-6999.20123354","article-title":"Correlation of red cell distribution width with the severity of coronary artery disease: a large Chinese cohort study from a single center","volume":"126","author":"Ma FL","year":"2013","journal-title":"Chinese medical journal"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1208500"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)92719-I"},{"key":"e_1_2_6_31_1","unstructured":"Merck.2012. Merck announces HPS2\u2010THRIVE study of Tredaptive\u2122 (Extended\u2010Release Niacin\/Laropiprant) did not achieve primary endpoint)."},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780199232178.001.0001"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.11.2877"},{"key":"e_1_2_6_34_1","first-page":"167","article-title":"Hemorheology of growth hormone\u2010deficient adults","volume":"20","author":"Peyreigne C","year":"1999","journal-title":"Clin Hemorheol Microcirc"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1159\/000112639"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.83.6.2104"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2006.088096"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.2007.065003"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.2008.086553"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1206797"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03345745"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.47.2.159"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa065485"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0b013e32835b7296"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-11-108"}],"container-title":["American Journal of Human Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajhb.22568","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajhb.22568","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ajhb.22568","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajhb.22568","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T12:01:42Z","timestamp":1716811302000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajhb.22568"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,7]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,9,10]]}},"alternative-id":["10.1002\/ajhb.22568"],"URL":"https:\/\/doi.org\/10.1002\/ajhb.22568","archive":["Portico"],"relation":{},"ISSN":["1042-0533","1520-6300"],"issn-type":[{"value":"1042-0533","type":"print"},{"value":"1520-6300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,7]]}}}