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Moderate\u2010to\u2010vigorous physical activity was assessed by accelerometry and children were classified as active (\u226560 min\/day) or insufficiently active (&lt;60 min\/day). Static strength was expressed as the ratio of handgrip strength\/body weight and used to classify children as having high (\u2265P50) or low (&lt;P50) muscular strength. Children were classified into four groups: active and high strength, active and low strength, insufficiently active and high strength, insufficiently active and low strength. A continuous metabolic risk score was computed from cardiometabolic risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In general, the insufficiently active and low strength group had the worst metabolic risk score, and the active and high strength group had the best. Significant differences were found within physical activity groups for metabolic risk: children classified as \u201cactive and high strength\u201d and \u201cinsufficiently active and high strength\u201d had better metabolic risk scores than \u201cactive and low strength\u201d and \u201cinsufficiently active and low strength\u201d, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Muscular strength has a relevant role in attenuating the association between physical inactivity and metabolic risk in children; a further benefit was identified in children with high physical activity and high muscular strength.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajhb.22904","type":"journal-article","created":{"date-parts":[[2016,8,22]],"date-time":"2016-08-22T10:42:57Z","timestamp":1471862577000},"source":"Crossref","is-referenced-by-count":31,"title":["Active and strong: physical activity, muscular strength, and metabolic risk in children"],"prefix":"10.1002","volume":"29","author":[{"given":"Thayse Natacha","family":"Gomes","sequence":"first","affiliation":[{"name":"CIFI<sup>2<\/sup>D, Kinanthropometry Lab, Faculty of Sport University of Porto Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda Karina","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Department of Physical Education Federal University of Vi\u00e7osa Vi\u00e7osa MG Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter T.","family":"Katzmarzyk","sequence":"additional","affiliation":[{"name":"Pennington Biomedical Research Center, Louisiana State University Baton Rouge LA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Maia","sequence":"additional","affiliation":[{"name":"CIFI<sup>2<\/sup>D, Kinanthropometry Lab, Faculty of Sport University of Porto Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,8,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2008.047142"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69075-2"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5448.2011.00769.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-89102007000100010"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e318230e441"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000000486"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1203\/01.pdr.0000185272.46705.18"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2009.058321"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0093150"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-0443"},{"key":"e_1_2_6_12_1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1475-2840-7-17","article-title":"On the use of a continuous metabolic syndrome score in pediatric research","volume":"7","author":"Eisenmann J. 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