{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T17:48:16Z","timestamp":1777571296107,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Hum Biol"],"published-print":{"date-parts":[[2017,5,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the ability of BMI, WC, and WHtR to identify increased cardiometabolic risk in pre\u2010adolescents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a cross\u2010sectional study involving 192 children (10.92\u2009\u00b1\u20090.58 years, 56% female) from the United Kingdom between 2010 and 2013. Receiver operating characteristic curves determined the discriminatory ability of BMI, WC and WHtR to identify individuals with increased cardiometabolic risk (increased clustered triglycerides, HDL\u2010cholesterol, systolic blood pressure, cardiorespiratory fitness, and glucose).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A WHtR\u2009\u2265\u20090.5 increased the odds by 5.2 (95% confidence interval 2.6 \u2010 10.3) of having increased cardiometabolic risk. Similar associations were observed for BMI and WC. Both BMI\u2010z and WHtR were fair predictors of increased cardiometabolic risk, although BMI\u2010z demonstrated the best trade\u2010off between sensitivity and specificity, 76.1% and 63.6%, compared with 68.1% and 65.5% for WHtR. Cross\u2010validation analysis revealed that BMI\u2010z and WHtR correctly classified 84% of individuals (kappa score\u2009=\u20090.671, 95% CI 0.55, 0.79). The sensitivity of the cut\u2010points suggests that 89.3% of individuals were correctly classified as being at risk with only 10.7% misdiagnosed whereas the specificity of the cut\u2010points indicated that 77.8% of individuals were correctly identified as being healthy with 22.2% of individuals incorrectly diagnosed as being at risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Findings suggest that WHtR provides similar cardiometabolic risk estimates to age and sex adjusted BMI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajhb.22934","type":"journal-article","created":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T12:03:41Z","timestamp":1478001821000},"source":"Crossref","is-referenced-by-count":4,"title":["Utility of three anthropometric indices in assessing the cardiometabolic risk profile in children"],"prefix":"10.1002","volume":"29","author":[{"given":"Duncan S.","family":"Buchan","sequence":"first","affiliation":[{"name":"Institute of Clinical Exercise and Health Science, University of the West of Scotland Lanarkshire Hamilton ML3 0JB United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynne M.","family":"Boddy","sequence":"additional","affiliation":[{"name":"The Physical Activity Exchange Research Institute for Sport and Exercise Sciences, Liverpool John Moores University 62 Great Crosshall Street Liverpool L3 2AT United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fergal M.","family":"Grace","sequence":"additional","affiliation":[{"name":"Institute of Clinical Exercise and Health Science, University of the West of Scotland Lanarkshire Hamilton ML3 0JB United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elise","family":"Brown","sequence":"additional","affiliation":[{"name":"School of Health Sciences Oakland University 2200 N. Squirrel Road Rochester Michigan 48309\u20104401"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Sculthorpe","sequence":"additional","affiliation":[{"name":"Institute of Clinical Exercise and Health Science, University of the West of Scotland Lanarkshire Hamilton ML3 0JB United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Conor","family":"Cunningham","sequence":"additional","affiliation":[{"name":"School of Medicine, Dentistry and Biomedical Sciences Queens University Belfast Health Sciences Building, 97 Lisburn Road Belfast BT9 7BL United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie H.","family":"Murphy","sequence":"additional","affiliation":[{"name":"Sport and Exercise Sciences Research Institute, Ulster Sports Academy, Ulster University Jordanstown Campus, Shore Road, Newtownabbey Co. Antrim BT37 0QB United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Dagger","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Liverpool Hope University Hope Park Liverpool L16 9JD United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence","family":"Foweather","sequence":"additional","affiliation":[{"name":"The Physical Activity Exchange Research Institute for Sport and Exercise Sciences, Liverpool John Moores University 62 Great Crosshall Street Liverpool L3 2AT United Kingdom"},{"name":"Department of Sport and Physical Activity Edge Hill University St Helens Road Ormskirk L39 4QP"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee E. 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