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Cold exposure increased the Tuvans' energy expenditure by (mean\u2009\u00b1\u2009<jats:italic>SD<\/jats:italic>) 0.9\u2009\u00b1\u20090.7\u2009kJ\u2009min<jats:sup>\u22121<\/jats:sup> and the Europeans' by 1.3\u2009\u00b1\u20091.54\u2009kJ\u2009min<jats:sup>\u22121<\/jats:sup>; these changes were not significantly different. The forearm\u2010fingertip skin temperature gradient of the Tuvans was lower, indicating less vasoconstriction, than the Europeans during the cold exposure (0\u2009\u00b1\u20094.5\u00b0C vs. 8.8\u2009\u00b1\u20092.7\u00b0C). A CIVD response occurred in 92% of the Tuvans and 36% of the Europeans. In line, finger temperature during the CIVD test was higher in the Tuvans than the Europeans (13.4\u2009\u00b1\u20093.4\u00b0C vs. 3.9\u2009\u00b1\u20092.3\u00b0C).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cold\u2010induced thermogenesis and the onset of shivering were similar in both populations. However, vasoconstriction at the extremities was reduced in the Tuvans compared to the Europeans. The enhanced blood flow to the extremities could be beneficial for living in an extreme cold environment by improving dexterity, comfort, and reducing the risk of cold\u2010injuries.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajhb.23933","type":"journal-article","created":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T13:18:44Z","timestamp":1686748724000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Thermoregulation of Tuvan pastoralists and Western Europeans during cold exposure"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3547-3604","authenticated-orcid":false,"given":"Adam J.","family":"Sellers","sequence":"first","affiliation":[{"name":"Department of Nutrition and Movement Sciences, School of Nutrition and Translational Research in Metabolism (NUTRIM) Maastricht University  Maastricht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dolaana","family":"Khovalyg","sequence":"additional","affiliation":[{"name":"Laboratory of Integrated Comfort Engineering (ICE) \u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne (EPFL)  Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wouter","family":"van Marken Lichtenbelt","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Movement Sciences, School of Nutrition and Translational Research in Metabolism (NUTRIM) Maastricht University  Maastricht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1958.12.1.9"},{"key":"e_1_2_9_3_1","first-page":"108","article-title":"The influence of physical conditions in the genesis of species","volume":"1","author":"Allen J. 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