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At study entry, workstation dimensions and worker postures were measured and medical and psychosocial risk factors were assessed. Daily diaries were used to document work practices and incident MSS. Those reporting MSS were examined for specific MSD. Incidence rates of MSS and MSD were estimated with survival analysis. Cox regression models were used to evaluate associations between participant characteristics at entry and MSS and MSD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The annual incidence of N\/S MSS was 58 cases\/100 person\u2010years and of N\/S MSD was 35 cases\/100 person\u2010years. The most common N\/S MSD was somatic pain syndrome. The annual incidence of H\/A MSS was 39 cases\/100 person\u2010years and of H\/A MSD was 21 cases\/100 person\u2010years. The most common H\/A disorder was deQuervain's tendonitis. Forty\u2010six percent of N\/S and 32% of H\/A MSS occurred during the first month of follow\u2010up. Gender, age, ethnicity, and prior history of N\/S pain were associated with N\/S MSS and MSD. Gender, prior history of H\/A pain, prior computer use, and children at home were associated with either H\/A MSS or MSD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>H\/A and N\/S MSS and MSD were common among computer users. More than 50% of computer users reported MSS during the first year after starting a new job. Am. J. Ind. Med. 41:221\u2013235, 2002. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.10066","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T23:13:41Z","timestamp":1030317221000},"page":"221-235","source":"Crossref","is-referenced-by-count":384,"title":["A prospective study of computer users: I. 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