{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T04:13:06Z","timestamp":1784952786185,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2003,9,16]],"date-time":"2003-09-16T00:00:00Z","timestamp":1063670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Laboratory workers have long been suspected of having increased risks of cancer due to their occupation. We evaluated occupational exposure and cancer incidence among Finnish laboratory workers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The cohort was comprised of 4,722 laboratory workers reported to the Finnish Register of Workers Exposed to Carcinogens in 1979\u20131988. The standardized incidence ratios (SIR) for cancers and their 95% confidence intervals (CI) were calculated based on data of the Finnish Cancer Registry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The most common carcinogens, to which these workers were potentially exposed, were chromium (VI), carbon tetrachloride, cadmium, benzene, and chloroform. From this cohort, 174 persons were recorded with primary tumors in 1980\u20131999. The SIR for cancer of all sites combined was 0.99 (CI 0.85\u20131.14). None of the cancer\u2010specific SIRs were significantly elevated. Slight excesses were found, e.g., for non\u2010Hodgkin's lymphoma (seven observed, 4.8 expected) and leukemia (four observed, three expected).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study did not suggest any major cancer risks among Finnish laboratory workers but the follow\u2010up time of the cohort was too short (on an average 15.7 years) to reveal possible cancer risks requiring a longer induction period. Am. J. Ind. Med. 44:343\u2013350, 2003. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.10278","type":"journal-article","created":{"date-parts":[[2003,9,17]],"date-time":"2003-09-17T14:18:17Z","timestamp":1063808297000},"page":"343-350","source":"Crossref","is-referenced-by-count":41,"title":["Exposure to chemical carcinogens and risk of cancer among Finnish laboratory workers"],"prefix":"10.1002","volume":"44","author":[{"given":"Timo","family":"Kauppinen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eero","family":"Pukkala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Saalo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie J.","family":"Sasco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,9,16]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700130506"},{"issue":"2","key":"e_1_2_1_3_1","first-page":"1","article-title":"Occupational cancer in the Nordic countries","volume":"25","author":"Andersen A","year":"1999","journal-title":"Scand J Work Environ Health"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.1607"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1996.221"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)91938-Q"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0274(199803)33:3<247::AID-AJIM6>3.0.CO;2-T"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.61"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.51.5.295"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116431"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199205000-00012"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700200108"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.4.5992.329"},{"key":"e_1_2_1_14_1","first-page":"188","article-title":"Mortality study of British pathologists 1974\u20131980","volume":"41","author":"Harrington JM","year":"1984","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700210403"},{"key":"e_1_2_1_16_1","first-page":"501","volume-title":"Changes in cigarette\u2010related disease risks and their implication for prevention and control","author":"Hrubec Z","year":"1996"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1986.9937419"},{"key":"e_1_2_1_18_1","first-page":"253","article-title":"Occupational risks for intracranial gliomas in Sweden","volume":"78","author":"McLaughlin JK","year":"1987","journal-title":"J Natl Cancer Inst"},{"key":"e_1_2_1_19_1","first-page":"66","article-title":"Occupational risks for meningiomas of the CNS in Sweden","volume":"29","author":"McLaughlin JK","year":"1987","journal-title":"J Occup Med"},{"key":"e_1_2_1_20_1","first-page":"224","volume-title":"Occupational mortality, 1970\u20131972","author":"OPCS","year":"1978"},{"key":"e_1_2_1_21_1","volume-title":"Occupational mortality, 1979\u201380, 1982\u201383. Great Britain. Decennial supplement","author":"OPCS","year":"1986"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700250609"},{"key":"e_1_2_1_23_1","first-page":"277","volume-title":"Contributions to epidemiology and biostatistics","author":"Pukkala E","year":"1995"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0274(200012)38:6<651::AID-AJIM6>3.0.CO;2-J"},{"key":"e_1_2_1_25_1","first-page":"77","volume-title":"Occupational Health, Decennial Supplement. The registrar general's decennial supplement for England and Wales","author":"Roman E","year":"1995"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)90849-X"},{"key":"e_1_2_1_27_1","first-page":"34","volume-title":"International study of cancer risk in biology research laboratory workers in Europe","author":"Sasco AJ","year":"1992"},{"key":"e_1_2_1_28_1","first-page":"142","volume-title":"ASA 1998 (in Finnish)","author":"Savela A","year":"2000"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/81.19.1472"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/81.19.1480"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a115680"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.1998.00690.x"},{"key":"e_1_2_1_33_1","first-page":"1217","article-title":"Brain cancer and other causes of death in anatomists","volume":"77","author":"Stroup NE","year":"1986","journal-title":"J Natl Cancer Inst"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0274(199904)35:4<382::AID-AJIM9>3.0.CO;2-F"}],"container-title":["American Journal of Industrial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajim.10278","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.10278","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T18:55:26Z","timestamp":1700247326000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajim.10278"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,9,16]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,10]]}},"alternative-id":["10.1002\/ajim.10278"],"URL":"https:\/\/doi.org\/10.1002\/ajim.10278","archive":["Portico"],"relation":{},"ISSN":["0271-3586","1097-0274"],"issn-type":[{"value":"0271-3586","type":"print"},{"value":"1097-0274","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,9,16]]}}}