{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:49:26Z","timestamp":1790635766360,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2003,9,16]],"date-time":"2003-09-16T00:00:00Z","timestamp":1063670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>A prior investigation of this cohort of female nuclear workers found increased deaths from mental disorders, including dementia. The present study estimates the effect of workplace exposures to ionizing radiations and other hazards on mortality from dementia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A nested case\u2010control study within a pooled cohort of 67,976 female nuclear workers compared 91 cases of death from dementia with 910 controls. Adjusted odds ratios (ORs) were employed to estimate the effects of maximum annual and total lifetime radiation doses on the occurrence of dementia in 168 monitored workers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both maximum annual (OR\u2009=\u20092.11, 95% confidence interval (CI)\u2009=\u20090.98, 4.40) and total lifetime radiation doses (OR\u2009=\u20092.09, 95% CI\u2009=\u20091.02, 4.29) were associated with death from dementia. Significant dose\u2010response trends were present for both exposures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Occupational exposure to ionizing radiation (IR) may be associated with increased risk of death from dementia in female workers. Since these findings are based on a small number of cases, replication with a larger case sample should be pursued. Am. J. Ind. Med. 44:351\u2013358, 2003. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.10288","type":"journal-article","created":{"date-parts":[[2003,9,17]],"date-time":"2003-09-17T14:18:17Z","timestamp":1063808297000},"page":"351-358","source":"Crossref","is-referenced-by-count":22,"title":["Nested case\u2010control study of external ionizing radiation dose and mortality from dementia within a pooled cohort of female nuclear weapons workers"],"prefix":"10.1002","volume":"44","author":[{"given":"Ralph F.","family":"Sibley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth S.","family":"Moscato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregg S.","family":"Wilkinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nachimuthu","family":"Natarajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,9,16]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"289","article-title":"Reappraisal of brain tumor risk among US nuclear workers: A 10\u2010year review","volume":"16","author":"Alexander V","year":"2001","journal-title":"Occup Med"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043764-199804000-00012"},{"key":"e_1_2_1_4_1","volume-title":"Statistical models in epidemiology","author":"Clayton P","year":"1993"},{"key":"e_1_2_1_5_1","first-page":"249","article-title":"Toxic leukoencephalopathy","volume":"22","author":"Filley C","year":"1999","journal-title":"Clin Neuropharmacol"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1999.tb03842.x"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1359-6446(01)01867-0"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(00)01471-1"},{"key":"e_1_2_1_9_1","volume-title":"SPSS for Windows made simple: Release 10","author":"Kinnear P","year":"2000"},{"key":"e_1_2_1_10_1","volume-title":"Epidemiologic research","author":"Kleinbaum D","year":"1982"},{"key":"e_1_2_1_11_1","volume-title":"Cytel Software Corp.","author":"LogXact for Windows","year":"1996"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(99)00376-4"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006262918694"},{"issue":"8","key":"e_1_2_1_14_1","first-page":"39","article-title":"An epidemiological analysis of the health status of the participants in the cleanup of the aftermath of the accident at the Chernobyl atomic electric power station","author":"Ponomarenko VM","year":"1999","journal-title":"Lik Sprava"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199903000-00009"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1093\/oxfordjournals.aje.a113389","article-title":"Mental function following scalp irradiation during childhood","volume":"116","author":"Ron E","year":"1982","journal-title":"Am J Epidemiol"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1984.2.12.1327"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.86.9.1281"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100034016"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/153.4.309"},{"key":"e_1_2_1_21_1","unstructured":"STATA Version 7.2002. 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