{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T20:35:42Z","timestamp":1772742942419,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,1,15]],"date-time":"2004-01-15T00:00:00Z","timestamp":1074124800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2004,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Excess lung cancer mortality among the exposed Vermont granite workers has been reported. These studies were based on job and tenure surrogates, with the potential for misclassification and inability to evaluate quantitative exposure\u2010response.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Industrial hygiene data collected from 1924 to 1977 was analyzed in conjunction with mortality data to examine quantitative exposure\u2010response for silica, lung cancer, and other lung diseases. A person\u2010years analysis was undertaken by cumulative exposure group, including lagged and unlagged tabulations. Poisson models were fitted to untransformed and log transformed exposure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The results indicated a clear relationship of lung cancer, tuberculosis, pneumoconiosis, non\u2010malignant lung disease, and kidney cancer with cumulative exposure. An exposure to 0.05 mg\/m<jats:sup>3<\/jats:sup> from age 20 to 64 was associated with a lifetime excess risk of lung cancer for white males of 27\/1,000.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results of this study of workers exposed almost exclusively to silica and no other major occupational confounding exposures indicate a clear exposure\u2010response for lung cancer. Am. J. Ind. Med. 45:129\u2013138, 2004. Published 2004 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.10348","type":"journal-article","created":{"date-parts":[[2004,1,23]],"date-time":"2004-01-23T09:00:29Z","timestamp":1074848429000},"page":"129-138","source":"Crossref","is-referenced-by-count":55,"title":["Quantitative exposure\u2010response for silica dust and lung cancer in Vermont granite workers"],"prefix":"10.1002","volume":"45","author":[{"given":"Michael D.","family":"Attfield","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Costello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,1,15]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"73","article-title":"Twenty\u2010six years' experience with dust control in the Vermont granite industry","volume":"33","author":"Ashe HB","year":"1964","journal-title":"Ind Med Surgery"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2321"},{"key":"e_1_2_1_4_1","first-page":"881","article-title":"Comparison of crude and smoking\u2010adjusted standardized mortality ratios","volume":"27","author":"Blair A","year":"1985","journal-title":"J Occup Med"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.2307\/4581198"},{"key":"e_1_2_1_6_1","unstructured":"BreslowNE DayNE.1987.Statistical methods for cancer research. 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