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Beryllium sensitized individuals were offered evaluations for CBD. The sensitivity, specificity, and positive predictive value (PPV) of the Be\u2010LPT were determined, as was inter\u2010 and intra\u2010laboratory agreement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>False positives were calculated to be 1.09%, with a laboratory range of 0.00\u20133.35% for the 10\u2010year investigation. Be\u2010LPTs performed on inter\u2010laboratory split blood specimens from sensitized individuals showed a false negative rate of 31.7%. The intra\u2010laboratory repeatability of abnormal Be\u2010LPT results ranged from 80.4\u201391.9%. The sensitivity of the Be\u2010LPT was determined to be 0.683, with a specificity of 0.969. The PPV of one abnormal Be\u2010LPT was 0.253.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The Be\u2010LPT is efficacious in medical surveillance of beryllium\u2010exposed individuals. The PPV of the Be\u2010LPT is comparable to other widely accepted medical tests. Confirmation of an abnormal result is recommended to assure appropriate referral for CBD medical evaluation. Am. J. Ind. Med. 46:453\u2013462, 2004. 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