{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T11:01:06Z","timestamp":1776942066005,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,11,9]],"date-time":"2006-11-09T00:00:00Z","timestamp":1163030400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Chronic exposure to carbon disulfide (CS<jats:sub>2<\/jats:sub>) has been associated with hypertension, elevated cholesterol, arteriosclerosis, ischemic heart disease and related mortality, adverse nervous and reproductive health effects, and hearing impairment. This study assessed the hypertension risk for male rayon workers exposed to CS<jats:sub>2<\/jats:sub>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 251 rayon workers and 226 administrative clerks at two plants in Taiwan received health examination and interviews, and were compared for hypertension risk. On\u2010site CS<jats:sub>2<\/jats:sub> levels were measured.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The hypertension was more prevalent in the exposure group (43.4%) than in controls (7.1%) with greater impact on systolic blood pressure than diastolic. Multivariate logistic regression analysis showed a significant dose\u2013response relationship between hypertensive risk and cumulative exposure index (CEI) with an odds ratio of 15.1 for workers exposed to 343\u2013468 year\u2010ppm of CS<jats:sub>2<\/jats:sub>. The overall risk was elevated to 7.6 times higher for rayon workers. The risk increased significantly after more than 10 years of employment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study suggests that it takes a long exposure period to develop hypertension for rayon workers with CS<jats:sub>2<\/jats:sub> exposure. Am. J. Ind. Med. 50:22\u201327, 2007. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.20409","type":"journal-article","created":{"date-parts":[[2006,11,9]],"date-time":"2006-11-09T17:47:05Z","timestamp":1163094425000},"page":"22-27","source":"Crossref","is-referenced-by-count":13,"title":["Risk for hypertension in workers exposed to carbon disulfide in the viscose rayon industry"],"prefix":"10.1002","volume":"50","author":[{"given":"Shu\u2010Ju","family":"Chang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiou\u2010Jong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tung\u2010Sheng","family":"Shih","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzu\u2010Chieh","family":"Chou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fung\u2010Chang","family":"Sung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,12,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0048-9697(91)90107-P"},{"key":"e_1_2_1_3_1","first-page":"475","article-title":"Vascular changes in workers exposed to carbon disulfide","volume":"30","author":"Braeckman L","year":"2001","journal-title":"Ann Acad Med"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.6289"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(72)90112-3"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00409406"},{"key":"e_1_2_1_7_1","first-page":"287","article-title":"Effects of exposure to carbon disulfide on low\u2010density lipoprotein cholesterol concentration and diastolic blood pressure","volume":"49","author":"Egeland GM","year":"1992","journal-title":"Br J Ind Med"},{"issue":"4","key":"e_1_2_1_8_1","first-page":"20","article-title":"A cross\u2010sectional medical and industrial hygiene survey of workers exposed to carbon disulfide","volume":"7","author":"Fajen J","year":"1981","journal-title":"Scand J Work Environ Health"},{"key":"e_1_2_1_9_1","first-page":"93","article-title":"Excess mortality from coronary heart disease in viscose rayon workers exposed to carbon disulphide","volume":"10","author":"Hernberg S","year":"1973","journal-title":"Work Environ Health"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004200000186"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/50.1.43"},{"key":"e_1_2_1_12_1","first-page":"139","article-title":"The influence of chronic exposure to carbon disulfide on metabolism of catecholamines and serotonin in women","volume":"42","author":"Kuligowski D","year":"1996","journal-title":"Ann Acad Med Stetin"},{"key":"e_1_2_1_13_1","unstructured":"Law of Labor Safety and Health.1997. Council of Labor Affairs Executive Yuan. Taipei."},{"key":"e_1_2_1_14_1","first-page":"699","article-title":"Mortality in the US rayon industry","volume":"30","author":"MacMahon B","year":"1988","journal-title":"J Occup Med"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1994.9954988"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.55.7.468"},{"key":"e_1_2_1_17_1","first-page":"313","article-title":"Coronary heart disease among workers exposed to carbon disulphide","volume":"27","author":"Partanen T","year":"1970","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_18_1","first-page":"291","article-title":"A mortality study of workers with reported chronic occupational carbon disulfide poisoning","volume":"9","author":"Peplonska B","year":"1996","journal-title":"Int J Occup Med Environ Health"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1006\/rtph.1997.1107"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459989210600611"},{"key":"e_1_2_1_21_1","first-page":"257","article-title":"Concentration of dopamine in plasma, activity of dopamine beta\u2010hydroxylase in serum and urinary excretion of tree catecholamines and vanilly mandelic acid in women chronically exposed to carbon disulphide","volume":"7","author":"Stanosz S","year":"1994","journal-title":"Int J Occup Med Environ Health"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00383365"},{"key":"e_1_2_1_23_1","first-page":"220","article-title":"Exposure to carbon disulphide and ischemic heart disease in a viscose rayon factory","volume":"44","author":"Sweetnan PM","year":"1987","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/21.4.745"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02492688"}],"container-title":["American Journal of Industrial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajim.20409","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.20409","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T08:02:43Z","timestamp":1694678563000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajim.20409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12,11]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["10.1002\/ajim.20409"],"URL":"https:\/\/doi.org\/10.1002\/ajim.20409","archive":["Portico"],"relation":{},"ISSN":["0271-3586","1097-0274"],"issn-type":[{"value":"0271-3586","type":"print"},{"value":"1097-0274","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,12,11]]}}}