{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T19:07:24Z","timestamp":1774120044776,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2008,5,5]],"date-time":"2008-05-05T00:00:00Z","timestamp":1209945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Beryllium use at the Nevada Test Site (NTS) was not acknowledged until the late 1990's. Subsequently, the ongoing U.S. DOE funded medical screening program, which began in 1998, started testing former workers of the NTS for beryllium sensitization (BeS) in 2001 to identify individuals who may be at higher risk of developing chronic beryllium disease (CBD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An observational study was conducted to identify work\u2010related factors associated with the odds of having BeS. Work history questionnaires were administered and principal components analysis was used to identify categories of related tasks associated with BeS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 1,786 former workers tested for BeS, 23 had a confirmed positive result. An increased risk of BeS was found among workers who performed cleanup (OR\u2009=\u20092.68, 95% CI: 1.10, 6.56) and those who worked in Building B where beryllium parts were machined (OR\u2009=\u20092.52, 95% CI: 1.02, 6.19), though no significant increased risk was found when categories of related tasks were used. Additionally, the number of years worked at the NTS was associated with increased risk of BeS. There was no difference in pulmonary function, chest X\u2010ray abnormalities, or respiratory symptoms between those who were sensitized and normal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The prevalence of BeS among former workers of the NTS who participated in our screening program was 1.3%. Former workers who performed specific job tasks may be at greater risk of developing BeS. Am. J. Ind. Med. 51:512\u2013523, 2008. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ajim.20585","type":"journal-article","created":{"date-parts":[[2008,5,5]],"date-time":"2008-05-05T15:16:28Z","timestamp":1210000588000},"page":"512-523","source":"Crossref","is-referenced-by-count":11,"title":["Beryllium sensitization and lung function among former workers at the Nevada Test Site"],"prefix":"10.1002","volume":"51","author":[{"given":"Ema G.","family":"Rodrigues","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael D.","family":"McClean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janice","family":"Weinberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lewis D.","family":"Pepper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,5,5]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"68854","article-title":"Chronic beryllium disease prevention program. Office of Environment, Safety and Health, Department of Energy","volume":"64","author":"United States Department of Energy (US DOE)","year":"1999","journal-title":"Final rule. Fed Regist"},{"key":"e_1_2_1_3_1","first-page":"1285","article-title":"Standardization of spirometry\u20141987 update","volume":"136","author":"American Thoracic Society (ATS)","year":"1987","journal-title":"Statement of the American Thoracic Society"},{"key":"e_1_2_1_4_1","unstructured":"Agency for Toxic Substances Disease Registry (ATSDR).2002.Toxicological profile for beryllium. 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