{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T02:43:01Z","timestamp":1711420981802},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2009,1,16]],"date-time":"2009-01-16T00:00:00Z","timestamp":1232064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2009,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>From 1950 to 1990 pentachlorophenol (PCP) was used widely in the New Zealand sawmill industry, and persistent claims of long\u2010term health effects have been made.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We surveyed surviving members of a cohort enumerated to study mortality in sawmill workers employed from 1970 to 1990. Estimates of historical exposure were based on job titles held, using the results of a PCP biomonitoring survey conducted in the 1980s. The survey involved interviews and clinical examinations, with interviewers and examiners blinded to exposure status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 293 participants 177 had not been exposed, and of the 116 exposed all but 10% had low or short\u2010term PCP exposure. Nevertheless, a number of significant associations between PCP exposure and the prevalence of various symptoms were observed including associations between: (i) exposure levels and self\u2010reported tuberculosis, pleurisy or pneumonia (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01) and a deficit in cranial nerve function (<jats:italic>P<\/jats:italic>\u2009=\u20090.04); (ii) duration of employment and thyroid disorders (<jats:italic>P<\/jats:italic>\u2009=\u20090.04), and neuropsychological symptoms including often going back to check things (<jats:italic>P<\/jats:italic>\u2009=\u20090.04), low libido (<jats:italic>P<\/jats:italic>\u2009=\u20090.02) and heart palpitations (<jats:italic>P<\/jats:italic>\u2009=\u20090.02), and a strong dose\u2013response trend for frequent mood changes without cause (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01); and (iii) cumulative exposure and frequent mood changes without cause (<jats:italic>P<\/jats:italic>\u2009=\u20090.02), low libido (<jats:italic>P<\/jats:italic>\u2009=\u20090.04), and in the overall number of neuropsychological symptoms reported (<jats:italic>P<\/jats:italic>\u2009=\u20090.03).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PCP exposure was associated with a number of physical and neuropsychological health effects that persisted long after exposure had ceased. Am. J. Ind. Med. 52:271\u2013281, 2009. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.20677","type":"journal-article","created":{"date-parts":[[2009,1,16]],"date-time":"2009-01-16T17:10:22Z","timestamp":1232125822000},"page":"271-281","source":"Crossref","is-referenced-by-count":11,"title":["Morbidity in former sawmill workers exposed to pentachlorophenol (PCP): A cross\u2010sectional study in New Zealand"],"prefix":"10.1002","volume":"52","author":[{"given":"David","family":"McLean","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Eng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evan","family":"Dryson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Walls","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Harding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khoon Ching","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea't","family":"Mannetje","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lis","family":"Ellison\u2010Loschmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tania","family":"Slater","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phil","family":"Shoemack","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil","family":"Pearce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,1,16]]},"reference":[{"key":"e_1_2_1_2_1","volume-title":"Results by sector: New Zealand forest industries labour market analysis","author":"APR Consultants, 2005","year":"2005"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470773666"},{"key":"e_1_2_1_4_1","volume-title":"Toxicological Profile for Pentachlorophenol, In: U.S. Department of Health and Human Services, Public Health Division","author":"ATSDR","year":"2001"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780195092424.001.0001"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1993.9938399"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.141"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2165"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1179\/oeh.2001.7.3.189"},{"key":"e_1_2_1_10_1","first-page":"249","volume-title":"Developments in occupational medicine","author":"Hogstedt C","year":"1980"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.2307\/3434067"},{"key":"e_1_2_1_12_1","volume-title":"Occupational exposures in insecticides application, and some pesticides","author":"International Agency for Research on Cancer (IARC)","year":"1991"},{"key":"e_1_2_1_13_1","volume-title":"Polychlorinated dibenzo\u2010para\u2010dioxins and polychlorinated dibenzofurans","author":"International Agency for Research on Cancer (IARC)","year":"1997"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/096032719301200605"},{"key":"e_1_2_1_15_1","first-page":"390","volume-title":"Complex chlorinated hydrocarbons: Occupational exposure in the sawmill industry","author":"Kalliokoski P","year":"1990"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.20385"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/15298668591394347"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere"},{"key":"e_1_2_1_19_1","volume-title":"Health outcomes in former New Zealand timber workers exposed to pentachlorophenol (PCP). 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