{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:20:51Z","timestamp":1790662851506,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2009,6,16]],"date-time":"2009-06-16T00:00:00Z","timestamp":1245110400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Since previous studies have provided conflicting results, we investigated the relationship between the risk of benign asbestos\u2010related diseases and different aspects of asbestos exposure in previous asbestos workers who underwent low\u2010dose computed tomography (CT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>CT scans were carried out in 772 subjects. A questionnaire was employed to collect data on smoking habits and duration, peak and cumulative exposure, and time since first exposure to asbestos. Multiple logistic regression models with stepwise selection of variables were used to evaluate the associations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fourteen (1.8%) cases of asbestosis, 187 (24.2%) of pleural plaques (PP), and 50 (6.5%) of diffuse pleural thickening (DPT) were found. The significant risk factors were: cumulative exposure for asbestosis (<jats:italic>P<\/jats:italic> for trend\u2009=\u20090.004); time since first exposure (<jats:italic>P<\/jats:italic> for trend &lt;0.001), and peak exposure (<jats:italic>P<\/jats:italic> for trend &lt;0.001) for PP; and time since first exposure for DPT (<jats:italic>P<\/jats:italic> for trend\u2009=\u20090.024).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Parenchymal asbestosis and PP are associated with different aspects of asbestos exposure. DPT appears to be less specific for asbestos exposure. Am. J. Ind. Med. 52:596\u2013602, 2009. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.20713","type":"journal-article","created":{"date-parts":[[2009,6,16]],"date-time":"2009-06-16T14:04:58Z","timestamp":1245161098000},"page":"596-602","source":"Crossref","is-referenced-by-count":29,"title":["Asbestos exposure and benign asbestos diseases in 772 formerly exposed workers: Dose\u2013response relationships"],"prefix":"10.1002","volume":"52","author":[{"given":"Giuseppe","family":"Mastrangelo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria N.","family":"Ballarin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernesto","family":"Bellini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Bicciato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Zannol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Gioffr\u00e8","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Zedde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianna","family":"Tessadri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugo","family":"Fedeli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"Valentini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Scoizzato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Marangi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Lange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,6,16]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.151.5.883"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00517698"},{"key":"e_1_2_1_4_1","first-page":"305","article-title":"Occupational lung disease\u2014Past record and future trend using the asbestos case as an example","volume":"6","author":"Becklake MR","year":"1983","journal-title":"Clin Invest Med"},{"key":"e_1_2_1_5_1","volume-title":"Mineral fibers and health","author":"Becklake M","year":"1991"},{"key":"e_1_2_1_6_1","first-page":"23","article-title":"Radiological changes after withdrawal from asbestos exposure","volume":"36","author":"Becklake MR","year":"1979","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_7_1","first-page":"373","article-title":"Radiographic assessment of pleuropulmonary disease in asbestos workers: Posteroanterior, four view films, and computed tomograms of the thorax","volume":"41","author":"B\u00e9gin R","year":"1984","journal-title":"Br J Ind Med"},{"key":"e_1_2_1_8_1","volume-title":"Occupational lung disorders","author":"Browne K","year":"1994"},{"key":"e_1_2_1_9_1","first-page":"311","article-title":"Asbestos, asbestosis, and cancer: The Helsinki criteria for diagnosis anf attribution","volume":"12","author":"Consensus Report","year":"1997","journal-title":"Scand J Work Environ Health"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.3.1103"},{"key":"e_1_2_1_11_1","first-page":"17","article-title":"Radiographic abnormalities among asbestos\u2010cement workers. An exposure\u2010response study","volume":"129","author":"Finkelstein MM","year":"1984","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.150.2.269"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.54.8.549"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043764-199601000-00016"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700180602"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1539\/joh.K7002"},{"key":"e_1_2_1_17_1","volume-title":"Guidelines for the use of ILO International Classification of radiographs of pneumoconiosis. Rev. Edn. International Labour Office Safety and Health Series No. 22 (Rev 80)","author":"International Labour Office","year":"1980"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.52.1.20"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/21.6.1180"},{"key":"e_1_2_1_20_1","first-page":"637","article-title":"The consequences of exposure to asbestos dust in a wartime gas\u2010mask factory","volume":"30","author":"Jones JS","year":"1980","journal-title":"IARC Sci Publ"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.9.3.2727359"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1054\/bjoc.2000.1161"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.154.6.8970380"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqn018"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.144.1.9"},{"key":"e_1_2_1_26_1","first-page":"137","article-title":"Indicators of asbestos exposure in autopsy routine. Pleural plaques and occupation","volume":"74","author":"Mollo F","year":"1983","journal-title":"Med Lav"},{"key":"e_1_2_1_27_1","first-page":"1332","article-title":"Programmes de prevention chez les personnes exposees a l'amiante: Bilan des experiences en cours","volume":"16","author":"Paris C","year":"1999","journal-title":"Rev Mal Respir"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.781"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-069X-7-30"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2331031133"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.3.5618.574"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0274(199912)36:6<593::AID-AJIM1>3.0.CO;2-Z"}],"container-title":["American Journal of Industrial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fajim.20713","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ajim.20713","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T22:23:48Z","timestamp":1699914228000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ajim.20713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6,16]]},"references-count":31,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2009,8]]}},"alternative-id":["10.1002\/ajim.20713"],"URL":"https:\/\/doi.org\/10.1002\/ajim.20713","archive":["Portico"],"relation":{},"ISSN":["0271-3586","1097-0274"],"issn-type":[{"value":"0271-3586","type":"print"},{"value":"1097-0274","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,6,16]]}}}