{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T19:17:43Z","timestamp":1774120663365,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2009,10,22]],"date-time":"2009-10-22T00:00:00Z","timestamp":1256169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Accelerated loss of forced expiratory volume in 1\u2009s (FEV<jats:sub>1<\/jats:sub>) in an individual is considered an indicator of developing lung disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We investigated longitudinal FEV<jats:sub>1<\/jats:sub> slopes, calculated by simple linear regression, and adverse health outcomes after 10\u201330 years, among 1,428 chemical plant workers. Cases were defined by FEV<jats:sub>1<\/jats:sub> slopes below 5th percentile values for the cohort. Cases were matched with controls (107 pairs) for race, gender, smoking status, year of birth, age, height, and calendar year at first test. Matched pair statistics were used for comparisons.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cases had a higher proportion, compared to controls, of diagnosis of COPD or emphysema (17.8% vs. 1.9%, <jats:italic>P<\/jats:italic>\u2009=\u20090.0002), medication use for respiratory diseases (24.3% vs. 4.7%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001), dyspnea (15% vs. 3.7%, <jats:italic>P<\/jats:italic>\u2009=\u20090.0042), and wheezing or rhonchi on examination (10.3% vs. 1.9%, <jats:italic>P<\/jats:italic>\u2009=\u20090.0225).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Chemical plant workers who experienced accelerated FEV<jats:sub>1<\/jats:sub> declines experienced four to nine times as many adverse health conditions over 10\u201330 years. Am. J. Ind. Med. 52:909\u2013915, 2009. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.20764","type":"journal-article","created":{"date-parts":[[2009,10,22]],"date-time":"2009-10-22T17:55:55Z","timestamp":1256234155000},"page":"909-915","source":"Crossref","is-referenced-by-count":3,"title":["Excessive longitudinal FEV<sub>1<\/sub> decline and risks to future health: A case\u2013control study"],"prefix":"10.1002","volume":"52","author":[{"given":"Mei Lin","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bipin H.","family":"Avashia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Wood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward L.","family":"Petsonk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,10,22]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.3.2008084"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/1047-2797(96)00007-5"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.53.5.312"},{"key":"e_1_2_1_5_1","first-page":"81","volume-title":"Applied statistics and the SAS programming language","author":"Cody RP","year":"1997"},{"key":"e_1_2_1_6_1","first-page":"353","article-title":"Medical screening using periodic spirometry for detection of chronic lung disease","volume":"8","author":"Hankinson J","year":"1993","journal-title":"Occup Med State Art Rev"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.1.9712108"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.2006.031146"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200508-1344OC"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.5.2101039"},{"key":"e_1_2_1_11_1","unstructured":"NIOSH Safety and Health Topic: Spirometry Monitoring Technology.2008. 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