{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T08:35:46Z","timestamp":1768293346678,"version":"3.49.0"},"reference-count":38,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To examine whether the previously observed excess risk of male germ cell cancer in a cohort of car\u2010manufacturing workers can be attributed to occupational activities inside and\/or outside the car industry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A nested case\u2013control study among workers in six plants included 205 cases of germ cell cancer and 1,105 controls, individually matched by year of birth (\u00b12 years). Job periods of the individual occupational histories were coded based on the International Standard Classification of Occupations (ISCO) and the industrial classification of economic activities (NACE). Odds ratios (ORs) and corresponding 95%\u2010confidence intervals (CI) for ever\u2010never and cumulative employment were calculated by conditional multivariate logistic regression adjusted for cryptorchidism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Significantly increased risks were observed for machinery fitters and assemblers (A) (OR\u2009=\u20091.8, 95% CI 1.25\u20132.53) and \u201cworkers not elsewhere classified\u201d (OR\u2009=\u20092.10, 95% CI 1.27\u20133.54), but no trend was observed for employment duration in either occupational group. Stratification of job group A by metal\u2010cutting and non\u2010cutting jobs yielded ORs of 1.87 (95% CI 1.31\u20132.67) and of 1.24 (95% CI 0.68\u20132.28), respectively. Among \u201cplumbers, welders, sheet &amp; structural metal workers\u201d (adjusted OR 1.4, 95% CI 0.99\u20131.95) only \u201cstructural metal preparers and erectors\u201d showed a substantially increased risk (OR\u2009=\u20092.30; 95% CI 1.27\u20134.27).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our results do not fully explain the increased incidence of germ cell cancer in the cohort, but support previous findings showing increased risks among metal workers. These risks were most strongly pronounced in metal\u2010cutting activities. Am. J. Ind. Med. 53:1006\u20131018, 2010. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.20865","type":"journal-article","created":{"date-parts":[[2010,6,2]],"date-time":"2010-06-02T01:24:18Z","timestamp":1275441858000},"page":"1006-1018","source":"Crossref","is-referenced-by-count":3,"title":["Case\u2013control study of male germ cell tumors nested in a cohort of car\u2010manufacturing workers: Findings from the occupational history"],"prefix":"10.1002","volume":"53","author":[{"given":"Ingo","family":"Langner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nils","family":"Schmei\u00dfer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birte","family":"Mester","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Behrens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Gottlieb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Ahrens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,9,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000173266.49104.bb"},{"key":"e_1_2_7_3_1","volume-title":"Retrospective assessment of occupational exposure to carcinogens in epidemiologic case\u2010control studies. 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