{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:36:22Z","timestamp":1791851782926,"version":"4.3.4"},"reference-count":51,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,4,3]],"date-time":"2014-04-03T00:00:00Z","timestamp":1396483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>We evaluated mortality among 5,964 former U.S. commercial cockpit crew (pilots and flight engineers). The outcomes of a priori interest were non\u2010chronic lymphocytic leukemia, central nervous system (CNS) cancer (including brain), and malignant melanoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Vital status was ascertained through 2008. Life table and Cox regression analyses were conducted. Cumulative exposure to cosmic radiation was estimated from work history data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared to the U.S. general population, mortality from all causes, all cancer, and cardiovascular diseases was decreased, but mortality from aircraft accidents was highly elevated. Mortality was elevated for malignant melanoma but not for non\u2010chronic lymphocytic leukemia. CNS cancer mortality increased with an increase in cumulative radiation dose.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cockpit crew had a low all\u2010cause, all\u2010cancer, and cardiovascular disease mortality but elevated aircraft accident mortality. Further studies are needed to clarify the risk of CNS and other radiation\u2010associated cancers in relation to cosmic radiation and other workplace exposures. Am. J. Ind. Med. 57:906\u2013914, 2014. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.22318","type":"journal-article","created":{"date-parts":[[2014,4,3]],"date-time":"2014-04-03T17:22:24Z","timestamp":1396545744000},"page":"906-914","source":"Crossref","is-referenced-by-count":27,"title":["Mortality among a cohort of U.S. commercial airline cockpit crew"],"prefix":"10.1002","volume":"57","author":[{"given":"Lee C.","family":"Yong","sequence":"first","affiliation":[{"name":"Division of Surveillance Hazard Evaluations and Field Studies National Institute for Occupational Safety and Health CDC Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynne E.","family":"Pinkerton","sequence":"additional","affiliation":[{"name":"Division of Surveillance Hazard Evaluations and Field Studies National Institute for Occupational Safety and Health CDC Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James H.","family":"Yiin","sequence":"additional","affiliation":[{"name":"Division of Surveillance Hazard Evaluations and Field Studies National Institute for Occupational Safety and Health CDC Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeri L.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Division of Surveillance Hazard Evaluations and Field Studies National Institute for Occupational Safety and Health CDC Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James A.","family":"Deddens","sequence":"additional","affiliation":[{"name":"Division of Surveillance Hazard Evaluations and Field Studies National Institute for Occupational Safety and Health CDC Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,3]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"708","article-title":"The age 60 rule","volume":"75","author":"Aerospace Medical Association","year":"2004","journal-title":"Aviat Space Environ Med"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3357\/ASEM.3091.2011"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a008722"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.11328"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004032-200011000-00016"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1667\/0033-7587(2000)153[0526:AETCRD]2.0.CO;2"},{"key":"e_1_2_6_8_1","volume-title":"Statistical methods in cancer research: Volume II. 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