{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T07:32:00Z","timestamp":1789889520442,"version":"4.0.1"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,1,4]],"date-time":"2016-01-04T00:00:00Z","timestamp":1451865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Occupational exposure to solvents may lead to neurotoxicity and sleep disturbances. We aimed to investigate the association of occupational exposure to petroleum\u2010derived hydrocarbons with neurotoxicity and sleep disturbance symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included male workers handling\/distributing petroleum products (exposed, n\u2009=\u2009250) and electricians (non\u2010exposed, n\u2009=\u2009250) from two companies in Tlemcen (Algeria). Neurotoxicity was evaluated with the Q\u201016 questionnaire, and sleep disturbances with the Epworth and the Berlin questionnaires. Multivariable Poisson regression models with robust error variances were applied obtaining risk ratios (RR) and their 95% confidence interval (CI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, the prevalence of reported neurotoxicity and sleep disturbance symptoms was higher in exposed than in non\u2010exposed workers. Significant adjusted associations were observed for neurotoxicity, snoring, and excessive sleepiness (RR\u2009=\u20092.2, CI: 1.7\u20132.8; RR\u2009=\u20091.4; CI: 1.1\u20131.7; RR\u2009=\u20091.3, CI: 1.2\u20131.5, respectively). No significant associations were observed with the Epworth score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our questionnaire\u2010based cross\u2010sectional study suggests that exposure to petroleum\u2010derived hydrocarbons is associated with self\u2010reported sleep disturbances and neurotoxicity symptoms. Am. J. Ind. Med. 59:129\u2013136, 2015. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.22561","type":"journal-article","created":{"date-parts":[[2016,1,4]],"date-time":"2016-01-04T10:37:08Z","timestamp":1451903828000},"page":"129-136","source":"Crossref","is-referenced-by-count":8,"title":["Sleep disturbances and neurotoxicity in workers exposed to hydrocarbons. An observational study from Algeria"],"prefix":"10.1002","volume":"59","author":[{"given":"Samira","family":"Sekkal","sequence":"first","affiliation":[{"name":"Laboratory of Medical Toxicology \u201cToximed,\u201d Faculty of Medicine University Abou Bekr Tlemcen Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidia","family":"Casas","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care Centre Environment and Health KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nahida","family":"Haddam","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Toxicology \u201cToximed,\u201d Faculty of Medicine University Abou Bekr Tlemcen Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Bouhacina","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Toxicology \u201cToximed,\u201d Faculty of Medicine University Abou Bekr Tlemcen Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Scheers","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care Centre Environment and Health KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdesselam","family":"Taleb","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Toxicology \u201cToximed,\u201d Faculty of Medicine University Abou Bekr Tlemcen Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Nemery","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care Centre Environment and Health KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,4]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"American Conference of Governmental Industrial Hygienists.2010. \u201c2010 TLVs and BEIs R. 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