{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T08:02:58Z","timestamp":1769587378837,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Our objective was to assess the influence of shiftwork on change in endothelial function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This longitudinal study was conducted in 188 police officers (78.2% men). Shiftwork status (day, afternoon, night) was assessed objectively using daily Buffalo, NY payroll work history records. Brachial artery flow\u2010mediated dilation (FMD) was assessed using ultrasound. Mean change in FMD% between 2004\u20132009 and 2010\u20132015 was compared across shiftwork using analysis of variance\/covariance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, mean FMD% decreased from 5.74\u2009\u00b1\u20092.83 to 3.88\u2009\u00b1\u20092.11 over an average of 7 years among all officers; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001. Effect modification by gender was significant. Among men (but not women), those who worked day shifts had a smaller mean (\u00b1SE) decrease in FMD% (\u22120.89\u2009\u00b1\u20090.35) compared with those who worked the afternoon (\u22122.69\u2009\u00b1\u20090.39; <jats:italic>P<\/jats:italic>\u2009=\u20090.001) or night shifts (\u22122.31\u2009\u00b1\u20090.45; <jats:italic>P<\/jats:italic>\u2009=\u20090.020) after risk factor adjustment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Larger declines in endothelial function were observed among men who worked afternoon or night shifts. Further investigation is warranted. Am. J. Ind. Med. 59:1001\u20131008, 2016. Published 2016. This article is a U.S. Government work and is in the public domain in the USA<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.22611","type":"journal-article","created":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T11:32:01Z","timestamp":1464780721000},"page":"1001-1008","source":"Crossref","is-referenced-by-count":13,"title":["Shiftwork and decline in endothelial function among police officers"],"prefix":"10.1002","volume":"59","author":[{"given":"Luenda E.","family":"Charles","sequence":"first","affiliation":[{"name":"Health Effects Laboratory Division Biostatistics and Epidemiology Branch National Institute for Occupational Safety and Health Centers for Disease Control and Prevention Morgantown West Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Songzhu","family":"Zhao","sequence":"additional","affiliation":[{"name":"Health Effects Laboratory Division Biostatistics and Epidemiology Branch National Institute for Occupational Safety and Health Centers for 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