{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T05:44:09Z","timestamp":1777441449461,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,8,18]],"date-time":"2017-08-18T00:00:00Z","timestamp":1503014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Italian Ministry of Health"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Industrial Med"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this study was to describe the mortality of a cohort of asbestos\u2010cement workers in the largest plant in the most industrialized Italian region (Lombardy).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cohort study was carried out on 1818 subjects, corresponding to 47\u2009536.1 person\u2010years of observation. Standardized mortality ratios (SMRs) were computed for the major causes of death.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Increased SMRs were observed for pleural, peritoneal and lung cancers, and for asbestosis (SMR 26.73, 95% Confidence Interval (CI) 20.99\u201033.55; 9.15, 95%CI 5.00\u201015.34; 1.48, 95%CI 1.27\u20101.72; and 368.05, 95%CI 214.40\u2010589.29, respectively). No excess in mortality for laryngeal cancer was observed (SMR 0.70, 95%CI 0.30\u20101.39). An increased mortality for ovarian cancer (SMR 3.64, 95%CI 0.99\u20109.33) was observed, although it was not statistically significant. Among men, mortality for pleural malignant mesothelioma was observed to be related to the duration of exposure, though not to latency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results of this study are generally consistent with present knowledge. Conversely, our results do not support the hypothesis that pleural malignant mesothelioma risk indefinitely increases after exposure, suggesting instead that the alternative hypothesis of a risk plateau or decrease after a time since first exposure of more than 40 years is more consistent with the observed data.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ajim.22750","type":"journal-article","created":{"date-parts":[[2017,8,18]],"date-time":"2017-08-18T12:56:42Z","timestamp":1503061002000},"page":"852-866","source":"Crossref","is-referenced-by-count":19,"title":["Mortality in asbestos cement workers in Pavia, Italy: A cohort study"],"prefix":"10.1002","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8503-6560","authenticated-orcid":false,"given":"Enrico","family":"Oddone","sequence":"first","affiliation":[{"name":"Occupational Medicine Unit \u201cS. Maugeri,\u201d Department of Public Health Experimental and Forensic Medicine University of Pavia Pavia Italy"},{"name":"Hospital occupational medicine unit (UOOML) ICS Maugeri IRCCS Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Ferrante","sequence":"additional","affiliation":[{"name":"Department of Translational Medicine Unit of Medical Statistics and Cancer Epidemiology University of Eastern Piedmont, Novara, and CPO\u2010Piemonte Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Tunesi","sequence":"additional","affiliation":[{"name":"Department of Translational Medicine Unit of Medical Statistics and Cancer Epidemiology University of Eastern Piedmont, Novara, and CPO\u2010Piemonte Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corrado","family":"Magnani","sequence":"additional","affiliation":[{"name":"Department of Translational Medicine Unit of Medical Statistics and Cancer Epidemiology University of Eastern Piedmont, Novara, and CPO\u2010Piemonte Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,8,18]]},"reference":[{"key":"e_1_2_13_2_1","first-page":"325","article-title":"III italian consensus conference on malignant mesothelioma of the pleura. epidemiology, public health and occupational medicine related issues","volume":"106","author":"Magnani C","year":"2015","journal-title":"Med Lav"},{"key":"e_1_2_13_3_1","first-page":"205","article-title":"Pleural mesothelioma mortality in Italy: time series reconstruction (1970\u20102009) and comparison with incidence(2003\u20102008)","volume":"40","author":"Ferrante P","year":"2016","journal-title":"(In Italian). Epidemiol Prev"},{"key":"e_1_2_13_4_1","first-page":"64","article-title":"Time trend in mesothelioma and lung cancer risk in asbestos workers in Italy","volume":"40","author":"Magnani C","year":"2016","journal-title":"(In Italian). Epidemiol Prev"},{"key":"e_1_2_13_5_1","first-page":"3","article-title":"Twenty years of data in the 5th report of the italian national mesothelioma register","volume":"40","author":"Marinaccio A","year":"2016","journal-title":"(In Italian). Epidemiol Prev"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2016-104100"},{"key":"e_1_2_13_7_1","first-page":"340","article-title":"Geographical patterns of mesothelioma incidence and asbestos exposure in Lombardy","volume":"107","author":"Mensi C","year":"2016","journal-title":"Italy. 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